Associate Scientist, Biologics Purification

Location
San Francisco, CA, United States
Posted
Jun 03, 2021
Ref
5361-399-NB
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Position Overview

Nektar has an exciting opportunity for an Associate Scientist, Biologics Purification to join their team.

Participates in developing recombinant protein production process. Performs day-to-day hands on operation for development, optimization and characterization of protein purification process. Designs and executes purification process to recover recombinant proteins. Modifies and conjugates purified proteins. Analyzes and characterizes purified proteins or conjugated proteins using a variety of techniques i.e. HPLC, SDS-PAGE, IEF, etc. May be involved in technology transfer to CRO/CMO and oversee process development, scale-up and/or GMP production activities at CMOs. Reviews and/or authors the CMC sections of regulatory filing documents. This position contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs.

Responsibilities:

Works on problems of moderate scope in which analysis of situation or data requires a review of identifiable factors. Exercises judgment within defined procedures and practices to determine appropriate action. Normally receives general instructions on routine work, detailed instructions on new assignments. Designs and executes purification process to recover recombinant protein . Modifies and conjugates purified proteins. Analyzes and characterizes purified proteins or conjugated proteins using a variety of techniques i.e. HPLC, SDS-PAGE, IEF, etc. Performs day-to-day planning, execution and analysis of laboratory experiments independently with minimal supervisions. Defines complex problems, develops approaches and develops experiments with sound judgment. Interfaces with various departments and partners. Uses professional concepts and scientific knowledge to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways. Defines problems, develops approaches and develops experiments with sound judgment and some supervision. Puts work practices in context with larger team. Writes reports and protocols. Participates in the development of patent applications. Plans and coordinates activities with other team members. Writes and/or approves complex reports and protocols. Maintains knowledge of regulatory compliance requirements. May assist with implementing organizational systems, identifying capital equipment, and projecting resource requirements. May lead staff or a group, provides training as needed, and ensures adherence to company policies and quality requirements. May mentor or manage staff, provides training as needed, and ensures adherence to company policies and quality requirements.

Requirements:

A PhD in a scientific discipline is required. Equivalent experience may be accepted. A minimum of 1 years work experience in a research and/or development environment is required. Post-doctoral work may serve as experience. Exceptional non-PhDs with demonstrated capabilities and/or significant experience may also be considered. Must be able to demonstrate significant success in technical proficiency, scientific creativity, collaboration with others and independent thought. Must be current and active in field, while able to demonstrate expert knowledge in scientific principles and concepts both internally and externally with sustained performance and accomplishment. Excellent written and verbal communications and team work skills are essential. Must be able to clearly communicate scientific information both written and oral. Must be able to compose sound written work. Ability to present technical information to both technical and non-technical audiences is required. Must be able to demonstrate sound judgment. Must be able to demonstrate problem solving capabilities. Strong organizational skills are required. Good computer skills are required. Working knowledge of MS word, Excel, Power point is required. Experience working in an FDA regulated environment and knowledge of current GMPs as they apply to laboratory practices are highly desired. Experience with regulatory filings is a plus. Previous management experience is a plus. Must be willing to work as part of a team. Must be able to demonstrate good interpersonal skills.

Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function.

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.