Senior Scientist (Cancer Biology)
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.
The Senior Scientist will join the Cancer Biology research team within the Tumor Microenvironment Thematic Research Center (TME TRC) at Bristol-Myers Squibb (BMS) in Redwood City, CA, and aid in the advancement of early stage therapeutic targets at the intersection of tumor genetics and immuno-biology. This team is composed of cancer biologists who work closely with immunologists/immuno-oncologists and stroma biologists focused on developing therapeutic targets integrated across the tumor microenvironment. Our mission is to provide transformative therapeutics to cancer patients that improve response rates and durability to this challenging disease.
The qualified candidate is a highly motivated, interactive, and creative individual who possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. The candidate will be expected to effectively collaborate with colleagues in the oncology, immunology, immuno-oncology, protein engineering/antibody development and medicinal chemistry groups. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and key stakeholders.
A Bachelor's Degree with 12-15+ years or Master's Degree with 8-10+ years of relevant experience, with strong scientific knowledge and research experience in cancer biology, particularly immuno-oncology, and cellular and molecular biology is required. Industry experience required.
Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required.
Hands on experience in immuno-oncology techniques, including proficiency with multi-color flow cytometry, Luminex, primary immune cell functional assays is required.
Hands on experience with a wide range of in vitro cellular and biochemical assays, including cell culture, western blotting, ELISA, AlphaLISA, IncuCyte, cytotoxicity assays, qPCR, is required.
Experience with ex vivo pharmacology, including rodent handling and tissue processing for primary cell isolation and PD measurement is highly desired.
Knowledge of or exposure to assays or assay cascades to identify and optimize drug candidates is desired.
Proficiency in utilizing software such as GraphPad Prism, FlowJo, Microsoft Office etc. for data analysis and figure generation is required.
Excellent interpersonal skills with the ability to collaborate and interact effectively with colleagues is required.
Ability to mentor more junior scientists and colleagues on laboratory techniques and best practices is highly valued.
Attention to detail with excellent organizational and record keeping skills is required.
This position is located in Redwood City, CA. There will be less than 10% travel.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to firstname.lastname@example.org. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.