Director for Protein Sciences
Director for Protein Sciences
United States - California - Foster City
Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.
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Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.
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The Protein Therapeutics Department is seeking an experienced and exceptional director to lead our Protein Chemistry Group. The successful candidate will work in a collaborative environment to mainly support the recombinant protein needs from our small molecule drug discovery programs . He/she will be responsible for leading the team efforts in recombinant protein sample preparation to meet project needs in assays and screenings, biophysics characterization, structural and MOA studies. Gilead Sciences Inc. is a highly matrixed organization and the ability to work effectively across multiple function groups is a key attribute for this role. Experience in successful leading the development and execution of recombinant protein expression and purification strategy for programs in Immuno-Oncology and Virology field and a strong understanding of enzymology and protein structure-function relationship are highly desired.
Responsibilities and Technical Skills:
- Lead cross-functional Protein Chemistry Group to develop and execute recombinant protein expression, purification and characterization strategies to ensure delivery of samples of high quality that meet project needs
- Oversee the outsourcing activity of screening CROs, protocol transfer, production outsourcing and quality validation of protein samples for drug discovery programs
- Lead and direct group effort to identify, assess and implement new technologies to enhance our technical capability and working efficiency
- Excellent collaboration, communication, and interpersonal skills are required to work with Enzymology/Biophysics, High Throughput Discovery, crystallography structure team, Mass Spectrometry and Bioinformatics functions to create synergy in assisting drug discovery projects on their effort of assay setup and high throughput screening, lead identification and optimization and MOA studies
- Strong experimental background in supporting small molecule drug discovery programs, demonstrated experience in recombinant protein expression in E. coli, insect cell and mammalian expression system , and deep understanding of enzymology, protein biochemistry/biophysics and protein structural studies
- Must be able to work independently and effectively on multiple programs in a fast-paced matrixed environment
- Must be team and detail-oriented, motivated, and results focused.
PhD and/or post-doctoral training in the area of biochemistry, molecular biology or other related bioscience field with a minimum of 8-10 years of directly relevant biotechnology or pharmaceutical industry experience . Candidate must be detail-oriented with excellent organizational and communication skills who enjoys working in a fast-paced dynamic multi-disciplinary environment. Preference will be given to candidates with proven track record of success and a strong scientific background in protein enzymology, biochemistry, structural studies as well as group management .
Gilead Sciences is continuing to hire for all open roles. Our interview process may be conducted virtually, and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams.
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