Downstream Manufacturing Associate I

Location
South San Francisco, CA
Posted
Jun 02, 2021
Hotbed
Biotech Bay
Required Education
Associate Degree
Position Type
Full time

About Us:

Vaxart is a clinical-stage biotechnology company developing a range of oral recombinant vaccines based on its proprietary delivery platform. Vaxart vaccines are administered using convenient room temperature-stable tablets that can be stored and shipped without refrigeration and eliminate the risk of needle-stick injury.

Vaxart has demonstrated that its proprietary tablet vaccine delivery platform is suitable to deliver recombinant vaccines, positioning the company to develop oral versions of currently marketed vaccines and to design recombinant vaccines for new indications. Its development programs currently include tablet vaccines designed to protect against coronavirus, norovirus, seasonal influenza and respiratory syncytial virus (RSV), as well as a therapeutic vaccine for human papillomavirus (HPV), Vaxart’s first immuno-oncology indication.

Our mission is the promotion of global health through the development of effective vaccines that can be administered by tablet rather than by injection, providing for the simple and efficient distribution and administration of safe vaccines in any setting.

We are looking for a Downstream Manufacturing Associate to join our growing South San Francisco team!

* Please note that we cannot sponsor Visas at this time.

Summary:

The Downstream Manufacturing Associate performs Upstream and Downstream operations supporting senior associates in the execution of Drug Substance manufacturing operations. The Manufacturing Associate I, performs manufacturing operations using single-use technology (SUT) in the execution of buffer preparation, chromatography column packing and testing, chromatography, and tangential flow filtration activities. The Manufacturing Associate I communicates process updates and constraints to manufacturing senior associates, manufacturing lead, and management team when needed.

Responsibilities:

  • Perform and support buffer preparation, Upstream and Downstream Drug Substance GMP Manufacturing operations.
  • Helps to identify process improvements.
  • Helps to identify documentation improvements for Standard Operating Procedures (SOPs), batch records (BRs), material specifications, and other documentation needed for cGMP compliance.
  • Supports deviation investigations as needed.
  • Supports new technology implementations and procedures into downstream manufacturing.
  • Other duties as assigned.

Requirements:

  • Bachelor’s Degree in Biology, Chemistry, or related discipline or equivalent work experience.
  • Minimum of 1-2 years of experience in the biopharmaceutical industry.
  • Minimum of 1-2 years of experience in the manufacture of Bulk Drug Substance based on cell culture production.
  • Good interpersonal skills and attention to detail.
  • Experience with the set-up and operation of single-use Chromatography and TFF skids is preferred.
  • Demonstrated ability to work and communicate collaboratively with others.
  • Must have strong critical thinking skills, initiative, integrity, and strong interpersonal and leadership skills.
  • Excellent communication skills, both written and verbal.
  • Highly motivated, strict attention to detail, and the ability to multi-task and successfully execute tasks.
  • Ability to problem solve, think critically, and troubleshoot while working independently.
  • Knowledge of quality systems and cGMP operations is preferred.
  • Ability to safely lift 25 pounds.

Vaxart offers team members a competitive compensation and benefits package, including a bonus program, stock options, 401K with employer matching, tuition assistance, and work life balance.

Vaxart is an Equal Opportunity Employer and values diversity. We are committed to the principles of equal employment opportunity and affirmative action for all applicants and employees. Equal opportunity and consideration are afforded to all qualified applicants and employees in personnel actions, which include: recruiting and hiring, selection for training, promotion, rates of pay or other compensation, transfer, discipline, demotion, layoff or termination. Vaxart does not unlawfully discriminate on the basis of race, color, religion, sexual orientation, marital status, pregnancy, gender identity, gender expression, family medical history or genetic information, citizenship, national origin or ancestry, sex, age, physical or mental disability, medical condition, veteran status, military status, or any other basis protected by federal, state or local law, ordinance or regulation.