Scientist - Translational/Biomarker Development Immuno-Oncology
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Scientist – Translational Research, Immunomodulatory Group
The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.
The Scientist will join the Translational Development team at Bristol Myers Squibb in Redwood City, CA to deliver biomarker and mechanism of action data for immune targets in the tumor microenvironment.
The qualified candidate is a highly motivated, interactive, and creative individual to support development of immunomodulatory therapeutic targets. In addition, the successful candidate will demonstrate superb verbal and written communication, and should be capable of presenting scientific results to multidisciplinary teams and key stakeholders.
Responsibilities include, but are not limited to, the following:
Performing experiments to identify biomarkers.
Developing biomarker assays.
Performing pharmacodynamic assays to validate biomarkers.
Supporting mechanism of action studies by performing studies using primary human tumors and in vitro functional models.
Effectively collaborating with colleagues in the immunology, protein engineering, and biomarker groups.
A B.S. with 7+, or M.S. with 4+, or PhD with 0-2 years of relevant experience performing translational research related to immuno-oncology or immunology.
Experience with biomarker and assay development for clinical trials.
Demonstrated independence in experimental design, execution, data analysis, and troubleshooting.
Skills and experience:
Knowledge of assays utilizing human tumor samples and how they are applied to biomarker identification is required.
Hands on experience with a wide range of in vitro cellular immunological assays, including cell culture and functional immune assays is required.
Deep familiarity and experience with flow cytometry is critical.
Experience with assay development is required.
Experience with organoids and/or explant cultures is desired.
Experience with analysis of bioinformatic data is desired.
Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.
Works with team leads to document and report research findings
Ability to mentor more junior scientists and colleagues on best practices in the laboratory would be highly valued.
Attention to detail with excellent organizational and record keeping skills is a requirement.
Excellent interpersonal skills with the ability to interact effectively with people, internally and externally is required.
This position is located in Redwood City, CA and will be lab-based.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
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