AbbVie

Principal Research Scientist, Precision Medicine-Oncology

Employer
AbbVie
Location
South San Francisco, California
Posted
May 30, 2021
Ref
2107049
Required Education
Doctorate/PHD/MD
Position Type
Full time
About AbbVie
AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Principal Research Scientist, Precision Medicine-Oncology  

Abbvie is a global, research-based biopharmaceutical company with an expanding portfolio of oncology products.  In the San Francisco Bay Area, more than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work in the discovery and development of novel oncology therapies.  The Precision Medicine Oncology team strategizes the use and application of advanced methods to implement and evaluate biomarkers across translational efforts and clinical trials to further AbbVie’s innovative oncology pipeline. This opportunity in AbbVie’s Precision-Medicine Oncology team is based out of the AbbVie Bay Area site in South San Francisco.  

Position Description

We are seeking a highly motivated scientist with expertise in Immuno-Oncology or related field. In this role, you will join an experienced team and will work closely with the Precision Medicine Lead to implement biomarker efforts in support of Abbvie sponsored clinical trials. The ideal candidate will have experience in the development and execution of successful biomarker strategies in cancer and/or immunotherapy trials. 

Responsibilities:

  • Lead implementation of biomarker strategies for one or more clinical trials and serve as point of contact for all aspects of clinical biomarker strategy providing scientific expertise and leadership to programs
  • Partner with clinical, translational, and discovery groups to design high quality clinical biomarker strategies to deliver on project needs
  • Implement standardized and cutting edge tools to identify biomarkers to characterize drug mechanisms, define patient selection strategies, and support back translational research
  • Lead biomarker subteams to enable cross functional collaboration on biomarker implementation
  • Present biomarker proposals and analyses to cross-functional teams 
  • Author biomarker sections of protocols, ICFs, IRB responses, regulatory documents, and scientific publications
  • Pro-actively consult primary scientific literature, keeping current on state of art technologies and emerging concepts in immuno-oncology

Qualifications

Qualifications - External

Basic:

  • PhD, MD or PhD/MD degree in life sciences (oncology, immunology, pathology, molecular biology, cell biology) and 6+ years industry experience of biomarker research in a clinical setting, preferably related to immunology or cancer biology
  • Broad technical expertise in tumor cell biology, immune cell biology, and clinical trial design or execution
  • Demonstrated ability to generate original scientific proposals, solve difficult technical problems and champion new technologies to achieve project goals

Preferred:

  • Strong scientific background in tumor biology and immuno-oncology supported by publication record in these areas
  • Clinical development experience interacting with teams conducting clinical trials
  • Demonstrated leadership in translational sciences, employing pharmacodynamic, predictive and exploratory biomarkers
  • Experience in analysis of large datasets and knowledge of biostatistics
  • Experience in assay development, qualification and implementation of biomarker assays on diverse platforms including IHC/IF, gene expression profiling, flow cytometry
  • Companion diagnostics development experience is a plus
  • Effectively work in a cross-functional team environment, interacting with various levels within the organization as well as vendors/academic sites/KOLs
  • Organization, orientation to details, and effective time management with an ability to adapt to changing priorities
  • Excellent written and oral presentation skills in the English language

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
Yes, 5 % of the Time
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.