MSAT Research Associate I/II

Raleigh-Durham, NC, United States
May 29, 2021
Science/R&D, Research
Bio NC
Required Education
Bachelors Degree
Position Type
Full time
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit

GRAIL is seeking a Research Associate for the LabOps Manufacturing Sciences and Technology team (MSAT), who will be primarily responsible for manufacturing reagents and associated tasks to support GRAIL's Clinical and R&D laboratory workflows. The ideal candidate is a meticulous, outstanding teammate with hands-on laboratory experience. The candidate will be encouraged to partner with many functions of our organization - Automation, Product Development, LIMS, Quality, and Clinical Lab - to identify systems limitations, implement process improvements, write documentation, and be instrumental in the day to day operations of the GRAIL laboratories.

You Will:

• Execute on high complexity manufacturing and testing of in-house prepared and externally acquired reagents
• Execute on forecasted R&D and Clinical Lab experiments ranging from reagent evaluation and qualification to general data generation activities
• Execute on automated and manual sample preparation and NGS assays
• Be responsible for accurately recording work performed per GLP
• Support root cause analysis for materials failing QC
• Become a specialist in the materials used in the current production assays
• Ensure laboratory activities are performed in compliance with procedures and safety guidelines when handling, storing and disposing of hazardous or bio-hazardous materials

Your Background Should Include:

B.S required in a relevant field
1+ years of experience in Next Generation Sequencing assays and workflows preferred.
Experience with Automated sample preparation workflows is a plus
Familiarity with basic molecular biology laboratory techniques including but not limited to (e.g. pipetting, SPRI, PCR, qPCR)
Familiarity with nucleic acids extraction techniques and quantification devices (e.g., Nanodrop, Bioanalyzer, Fragment Analyzer, ddPCR) is a plus
Excellent partnership and teamwork skills
Outstanding written and verbal communication skillsSelf-directed, innovative, and creative problem solverGeneral digital literacy and proficiency in GSuite

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

GRAIL, Inc. and its affiliates and subsidiaries ("GRAIL") does not accept any liability for fees for resumes from recruiters or employment agencies ("Agency"), without a binding, written recruitment agreement between GRAIL and Agency describing the services and specific job openings ("Agreement"). GRAIL may consider any candidate for whom an Agency has submitted an unsolicited resume and explicitly reserves the right to hire those candidate(s) without any financial obligation to the Agency, unless an Agreement is in place. Any email or verbal contacts with any person within GRAIL is inadequate to create a binding agreement. Agencies without an Agreement are requested not to contact any hiring managers of GRAIL with recruiting inquiries or resumes. Agencies interested in partnering with GRAIL may contact GRAIL's HR Department through our Customer Service team .