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Associate Scientist: Biology

Employer
Terray Therapeutics
Location
Pasadena, CA, United States
Start date
May 28, 2021

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Discipline
Science/R&D, Biology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach

Job Details

Company Overview: Terray Therapeutics is a venture-backed biotechnology company leveraging our vast high-quality data to optimize the path from discovery to transformative therapeutics. Our approach delivers on the promise of computation to revolutionize drug discovery. Through our closed-loop wet lab discovery platform and data-rich AI, we overcome existing constraints on chemical data by systematically mapping the biochemical interactions of massive and diverse small molecule libraries to identify novel therapeutic compounds. Access to this quantitative data at scale allows us to intelligently navigate an infinitely extensible and highly diverse chemical space to efficiently design, discover and optimize small molecule therapeutics. Our internal development programs are focused on immunology. In addition to these programs we also work with leading pharmaceutical companies.

Our integrated computational platform, tNova, harnesses our novel affinity binding technology, tArray, unique resynthesis capabilities, and broad biology infrastructure. tArray is the foundation of our discovery engine. It enables us to screen hundreds of millions of compounds in minutes and return quantitative data on each compound. Vast, high purity, and high diversity compound libraries are rapidly iterated using best-in-class chemistry to unlock chemical insights at the scale necessary to power AI-driven drug discovery.

Position Summary: Terray Therapeutics is seeking a motivated, creative, and experienced cell biologist to join our biology team. The candidate will work with other scientists in the team to design and optimize a wide-range of biochemical and cell-based assays and implement these to evaluate hits from screens and drive lead optimization. The position will report to the Head of Biology.

The core responsibilities of this job will be
  1. Independently run biochemical and cell-based assays specific to therapeutic targets of interest
  2. Adapt assays for medium to high-throughput screening of small molecule hits from our affinity screens
  3. Analyze data and communicate results
  4. Support organization of lab and equipment as needed

Experience and Qualifications: Given the company's size, anticipated growth and fast-paced environment, the organization requires a scientist who is thoughtful, high energy and can work effectively with the biology team to further enhance our next generation drug discovery capabilities.

Part of Terray Therapeutics' success is nurtured by a hands-on work environment where everyone is accountable, everyone is vested in a vision of excellence, and everyone actively takes part in the success of the business. Terray Therapeutics supports a positive work environment comprised of engaged employees who feel appreciated, recognized and free to be creative.

Qualifications include:
  • BSc with 5+ years of research experience in the field of immunology, oncology, molecular biology, biochemistry or related field
  • Background in small molecule drug discovery required
  • Extensive hands-on experience with biochemical assays (eg: enzymatic or FRET assays) required
  • Extensive hands-on experience with cell culture and cell-based assays required, including reporter assays, gene expression, qPCR and ELISAs
  • Background in molecular biology techniques, expression construct design and reporter line generation a plus
  • Proficiency in primary cell isolation, differentiation and culture and flow cytometry a plus
  • Excellent organizational, interpersonal and communication skills and can thrive in a highly collaborative research environment
  • Demonstrated technical proficiency, ability to troubleshoot to solve problems and to deliver high quality data

She/he will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.

Company

Terray is a biotechnology company with the technology, data, and mindset to radically change the way we discover and develop small molecule therapeutics. We explore molecules and targets broadly and deeply with a sophisticated integration of ultra-high throughput experimentation, generative AI, biology, medicinal chemistry, automation, and nanotechnology. Everything the company does is grounded in an iterative approach, producing massive amounts of precise, purpose-built data that gets increasingly valuable with each cycle of design and experimentation. The company’s platform uniquely blends experimentation and computation to improve the cost, speed, and success rate of small molecule drug discovery and development.

Company info
Website
Location
750 Royal Oaks, Suite 100
Monrovia
CA
91016
United States

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