Associate Scientist / Senior Research Associate, cGMP Cell Line Development (Quality Control)

Location
San Diego, CA, United States
Posted
May 25, 2021
Ref
526MB
Hotbed
Biotech Beach
Required Education
Associate Degree
Position Type
Full time
Fate Therapeutics is seeking a highly motivated Quality Control Associate Scientist or Senior Research Associate with flow cytometry, cell culture, and assays experience to support iPSC Product Development team. This role will perform in-process flow cytometry testing, lot release testing, and raw material testing for iPSC master cell banks (MCB). Additionally, this role will participate in designing, troubleshooting QC testing, and method qualification. The successful candidate will be adept at executing analytical test methods, working with mammalian cell culture, and analyzing emerging data to assess the characteristics of hematopoietic and stem cell-based therapeutics. This is a full-time position reporting to the Manager, cGMP Cell Line Development and is located at our corporate headquarters in San Diego, CA.

Responsibilities
• Perform in-process control and lot release testing using flow cytometry and other cell-based assays
• Design and test flow panels as needed for new projects and help in drafting of SOPs and batch
records
• Thaw, expand, bank, and submit banked cells for testing to appropriate vendors
• Ensure proper and timely completion of testing and tasks as assigned
• Report results in detailed and organized presentations and reports
• Participate in cross-functional training and identifying and facilitating continuous improvements
• Participate in technical transfer, qualification, and validation protocols for QC assays
• Maintain instrumentation and equipment preventative maintenance and supporting documentation
in a cGMP compliant manner
• Onboard new materials and reagents and maintain inventory for quality control use

Qualifications
• M.S. or B.S. degree in a scientific discipline with minimum of 4 years of biotechnology, clinical, or
pharmaceutical laboratory experience is required. Position depends on experience.
• Hands on experimental skills with multi-color flow cytometry is required.
• 2+ years of aseptic cell culture experience, human blood, and blood products is required.
• Prior experience working in a regulated environment (e.g., GMP, GLP, or CLIA) is highly preferred.
• Strong scientific, analytical, problem solving, and communication skills as well as sound judgment,
with the ability to work both independently and effectively with others.
• Highly organized, detail oriented with excellent record keeping abilities, and computer proficiency.
• Ability to work independently in a high paced team environment, to prioritize activities from
multiple projects with little supervision.

Working Conditions and Physical Requirements
• Will require working with cells and cell lines of human and/or animal origin
• Occasional evening and weekend work will be required.
• 100% on-site work at corporate headquarters in San Diego, CA

The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. For consideration send cover letter and curriculum vitae to: careers@fatetherapeutics.com and reference job 526MB.

About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for patients with cancer. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company's immuno-oncology pipeline includes off-the-shelf, iPSC-derived natural killer (NK) cell and T-cell product candidates, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens using chimeric antigen receptors (CARs). Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.