Scientist, Bioconjugation Chemistry

Location
Greater Boston Area
Posted
May 27, 2021
Required Education
Bachelors Degree
Position Type
Full time

BioSpace has been engaged to help our client, a Cambridge-based preclinical company, looking to add a Scientist, Bioconjugation Chemistry to its team.

Position Specifics:                                                                        

  • Synthesize bioconjugates using established (e,g, lysine, endogenous cysteine, site-specific) chemistries and contribute to the development of new methodologies
  • Purify bioconjugates by different modes (e.g. SEC, affinity, UF/DF) using benchtop and automated (e.g. AKTA FPLC) methods
  • Characterize bioconjugates using multiple techniques (e.g. UV/Vis, HPLC, and MS)
  • Present written and oral reports to multidisciplinary teams
  • Contribute to the build-out and upkeep of an expanding laboratory through maintaining shared equipment, assisting with general laboratory housekeeping, and developing processes for improving workflow efficiency

Requirements:

  • BS/MS in organic chemistry, biochemistry, or a related field with at least 1-2 years research experience in a laboratory setting
  • Hands-on experience with chemical modification, purification, and characterization of proteins required
  • Previous hands-on experience with antibodies and antibody-drug conjugates is a plus
  • Enthusiasm for collaborating with multidisciplinary teams of chemists, protein engineers, and biologists
  • Proficiency with operating common laboratory equipment and maintaining laboratory infrastructure