Senior Research Associate, Gene Therapy

Location
Cambridge
Posted
May 25, 2021
Ref
4589716002
Required Education
Bachelors Degree
Position Type
Full time
JOB PURPOSE

Sana Biotechnology is seeking a creative and highly-motivated individual to join our Gene Therapy - Vector Design team. This individual will be responsible for advancing viral vector pipelines by generating and testing crucial research material in in vitro assays and performing IND-enabling preclinical experiments, while working closely with other members of the gene therapy and process development teams.

DUTIES AND RESPONSIBILITIES
  • Planning, designing and executing complex experiments
  • Working with complex primary cells and analyzing them via multi-color flow cytometry
  • Building genetic libraries of variants, using high-throughput molecular cloning methods
  • Working closely with other members of the gene therapy and process development teams to share and apply knowledge advancements
  • Reviewing and presenting data cross-functionally at department meetings and larger forums
  • Comply with standard laboratory practices and company policies, including strict notebook documentation and biosafety policies
  • Contribute to the overall Sana mission and culture

QUALIFICATIONS

Basic Qualifications
  • M.S. in biotechnology, molecular biology, biochemistry, protein chemistry, virology, immunology or related discipline with 3 years of relevant industry laboratory experience, with a focus towards gene therapy and/or high-throughput assays
  • Demonstrated expertise in mammalian primary cell cultures, and multi color flow cytometry
  • Independently and proactively able to design and execute experiments
  • Excellent bench skills with attention to detail and high standards for data integrity and quality
  • Adherence to rigorous standards of good lab practices, safety, and documentation
  • Ability to work as part of a multi-site team
  • Working safely in person on a predictable and regular in-person basis is an essential job function for this position and the Company requires that all individuals working in-person, subject to certain exceptions, be fully vaccinated against COVID-19.

Preferred Qualifications
  • Knowledge of multi-color flow cytometry principles and flow cytometry data analysis
  • Lentiviral vector production
  • Experience in molecular biology, including PCR, RT-qPCR, restriction digest/ligation, Gibson/Golden Gate assembly, plasmid prep

WORKING CONDITIONS

This is a laboratory bench role. No regular travel required

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The job description listed above is representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

The Company is committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.