Supply Chain Manager/ Associate Director/ Director

Location
South San Francisco, CA
Posted
May 25, 2021
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Contract

LOCATION: South San Francisco or REMOTE

DIVISION: Product/CMC                                            DEPARTMENT: CMC

REPORTS TO: Chief Technical Officer


Day One was founded to address a critical unmet need: children with cancer are being left behind in a cancer drug development revolution. Our name was inspired by the “The Day One Talk” that physicians have with patients and their families about an initial cancer diagnosis and treatment plan. We aim to re-envision cancer drug development and redefine what’s possible for all people living with cancer—regardless of age—starting from Day One. 

SUMMARY: 

The Supply Chain Manager/Associate Director/Director is responsible for developing and managing supplier relationships, and for defining and tracking material requirements including planning, controlling inventory, packaging, labelling, and distribution activities, while monitoring and reporting supply chain metrics. Under the general supervision of the Chief Technical Officer, the Supply Chain Manager/Associate Director/Director consistently assures appropriate inventory levels and production planning to ensure both industry-leading customer service levels and the agility to respond quickly to new opportunities without compromising CMC’s optimal use of capital

 

The scope of this role includes oversight of both internal activities at Day One and its contract development and manufacturing organizations (CDMOs), suppliers, testing laboratories, and logistics vendors.  The role is accountable with Quality Assurance ensuring that vendors are compliant with global regulations, prepared for potential Sponsor and Regulatory Inspections and that the appropriate processes, systems and activities are in place and performed to protect patient safety, product quality, and data integrity.

 

The successful candidate will have a strong understanding of pharmaceutical production, supply chain management, and GMP requirements. The candidate will also have experience in commercial product supply chain.  This expertise, along with a pharmaceutical manufacturing background and the organizational and interpersonal skills required to build and foster strong relationships with collaborators, will be needed for success. The ideal candidate will demonstrate the ability to be both detail oriented and to think strategically.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES:

 

  • Execute agreements with strategic suppliers with an emphasis on meeting and exceeding cost, quality, and delivery goals.
  • Identify and qualify (in collaboration with QA) suppliers with appropriate quality, capacity, and competitive pricing to support the highest possible service levels to CMC customers.
  • Develop and manage supplier relationship and negotiate (in collaboration with Finance) most favorable terms to support current demands, while assuring future requirements are met.
  • Engage actively in supplier performance management.
  • Identify supplier performance gaps and develop action plans to achieve desired performance levels.
  • Identify and initiate cost reduction opportunities.
  •  

    Planning:

  • Establish formal material planning processes for manufacturing
  • Establish a system to manage inventory and safety stock levels for both components and finished goods.
  • Create and implement tools and processes to support production planning with accurate and timely information.
  •  

    Service:

  • Be the “Go to” resource for Day One to determine the best value suppliers, sourcing plans, make vs. buy, lead-time optimization, etc.
  • Address concerns and issues from customer service, sales, and procurement relating to customer needs.
  • Proactively communicate/escalate supply issues in a timely manner.
  • Evaluate and recommend actions to improve upon customer deliveries.
  • Share information and provide reporting on key supply chain metrics.
  • Willingness to travel up to ~25% to support vendor and supplier relationships.
  •                                                                                         

    SUPERVISORY RESPONSIBILITIES:

  • Develop, lead, and execute sourcing strategies with consideration and results for end-to-end supply chain excellence through technical collaboration, product introduction, cost modeling, logistics, manufacturing, quality control, ordering/distribution, integration and reusability.
  • Assure effective teamwork and results within the company by leading the coordination of efforts across functions.
  • Coordinate with commercial, R&D, and finance to ensure adequate supply and flow of materials.
  • Lead the logistics from production through packaging/labelling, and distribution of clinical and commercial product.
  •  

    EDUCATION/EXPERIENCE/SKILLS: 

     

    Education:

    ·       Minimum BS degree in Science or Engineering, advanced degree a plus

    Experience:

  • 5+ years of applicable pharmaceutical manufacturing experience.

  • Knowledge/Skills/Abilities:

    ·       Strong working knowledge of global GMP requirements, regulations, and guidance; sound judgment and commitment to ethical conduct.

    ·       Must have proven inventory and production planning experience

    ·       Experience with logistics supervision

    ·       Excellent leadership skills including an effective written and oral communicator, including experience preparing and making presentations to executive level management and interacting effectively with internal and external organizations, collaborators, and customers.

    ·       Proven track record of people management

     

    JOB COMPLEXITY:

    ·       Works on assigned problems of complex scope with analysis of situation or data required

    ·       Exercises judgment within defined procedures and practices to determine appropriate action

    ·       Builds productive internal and external working relationships

    ·       Uses professional concepts and company’s policies and procedures to solve a variety of routine problems.

     

    DISCLAIMER


    The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.  It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.