Research Associate, New Modality Genome Editing

Brisbane, CA, United States
May 24, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Mammoth Biosciences is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. By leveraging its internal research and development and exclusive licensing to patents related to Cas12, Cas13, Cas14 and CasPhi, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Mammoth is democratizing disease detection with easy and affordable point-of-care tests that allow real-time and simultaneous detection of multiple conditions, along with high-throughput tests that allow for unprecedented testing volume. Further, the company is transforming disease treatment with its proprietary micro-sized CRISPR proteins that enable new editing and delivery options. Based in San Francisco, Mammoth Biosciences is co-founded by CRISPR pioneer Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Decheng, Mayfield, NFX, and 8VC, and leading individual investors including Brook Byers, Tim Cook, Bob Nelsen, and Jeff Huber. At Mammoth, we are passionate about transforming lives through innovation.


Mammoth is currently seeking a talented and detail-oriented Research Associate with experience in molecular biology, flow cytometry, and/or mammalian cell culture to join our growing genome editing team. The successful candidate will work closely and collaboratively with colleagues to design/develop, perform and execute experiments on mammalian cell lines to support pipeline projects to develop Cas nucleases for genome editing and other applications. They will have the opportunity to contribute broadly across multiple technical areas. The position requires adaptability, excellent planning, strong organizational and communication skills, as well as the ability to work independently in a fast-paced team-oriented and dynamic environment.

    • Execution of molecular biology, cloning, cell culture and a broad range of functional assays.
    • Provide team support for basic laboratory tasks including tissue culture of various cell lines, phenotyping and analytical characterization of cells, genome editing of human cells, and virus production
    • Accurately and timely record, document, analyze and communicate laboratory data to senior staff and team members
    • Conducts all activities in a safe and efficient manner, and adheres to site environmental health and safety (EHS) requirements

    • Bachelor's degree in molecular and cell biology, immunology, biochemistry, or a related field
    • 3 years of relevant laboratory research experience
    • Experience in molecular cloning

    • Industry work experience
    • Familiarity with gene editing and/or CRISPR/Cas9
    • Proficiency in mammalian cell culture, PCR, qPCR, genomic DNA and mRNA purification, NGS sequencing, ELISA, western blot, retroviral/lentiviral/AAV transduction
    • Strong organizational and record-keeping skills, excellent interpersonal, verbal, and written communication skills. Highly motivated with a strong work ethic. Ability to work efficiently and productively in a fast-paced highly collaborative team environment
    • Knowledge of Microsoft Office Suite and other relevant data analysis software (Flowjo, GraphPad Prism, etc.)

    • Company-paid health/vision/dental benefits
    • Unlimited vacation and generous sick time
    • Company-sponsored meals and snacks
    • Wellness, caregiver and ergonomics benefits
    • 401(k) with company matching

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.