Manager, Process Sciences

Arranta Bio
Watertown, MA
May 22, 2021
Required Education
Position Type
Full time


Arranta Bio is a rapidly growing and dynamic bio-pharmaceutical contract development and manufacturing organization (CDMO). Our vision is to be the best in class CDMO providing development and GMP manufacturing services to microbiome innovators within the pharmaceutical industry. Therapies focused on the human microbiome are exhibiting incredible potential towards revolutionizing disease etiology and associated medical treatments. Arranta Bio’s mission is to build a world class organization which provides microbiome bio-pharmaceutical innovators with a single source of supply from early process development through clinical and commercial GMP finished product.


Arranta hires people who are committed and passionate to the goal of bringing life enhancing products to patients. We want top talent who will render ideas and a relentless desire towards accomplishing our mission; when a job becomes a passion, it makes you feel ALIVE.

Here at Arranta Bio, we embrace ALIVE – our core values that we live and breathe daily! We are Agile, Leading, Innovating, Value Creating, and Engaging.

We embrace our challenges as opportunities.

We are empowered to think and act.

We never settle; we strive to improve through purposeful creativity.

We build aligned teams who learn, grow, and deliver.

We are committed to building strong relationships.

Are you ready to come ALIVE with a daring and intrepid team?  Don’t wait another minute; Apply today!


 The Process Sciences Manager will lead a team of scientists performing early to late stage process development for plasmid manufacturing. He/She will design, perform, and interpret complex experiments supporting development plans and establishing robust, controlled manufacturing processes. They will have extensive understanding of microbiology, fermentation, and/or DNA purification technology and process. The Manager will lead a team of technical personnel as well as work collaboratively in a cross-functional team supporting ongoing development and tech transfer of processes from clients and into GMP manufacturing. The Process Sciences Manager will be responsible for technical/scientific aspects process development as well as for organizational leadership including training, leading, and continuously improving the process development team.


  • Lead day-to-day process development experiments and operations for plasmid process sciences team
  • Design and execute complex experiments and development activity, interpret and present data internally and externally to clients
  • Provide key technical leadership on cross-functional teams supporting plasmid process platform development and for client programs
  • Utilized DOE and QbD principles to ensure expedient, robust, and quality processes are deployed
  • Ensure process sciences laboratory and staff maintain a safety-first environment
  • Lead a variety of aspects in the development, optimization, and scale-up of bacterial fermentation and purification processes for plasmid
  • Build, train, lead, ensure a continuously improvement culture with respect to Safety, Quality, Delivery, and cost process development/sciences staff
  • Other duties as assigned

Experience and Skills


  • PhD or M.S. Degree in Biology, Biochemistry, Chemical Engineering, or related field
  • 8+ years of process development experience
  • 5+ years of leadership experience
  • Experience in fermentation/upstream development and/or DNA purification techniques preferred
  • Excellent verbal and written communications skills required
  • Advanced skills in experimental design (e.g. DOE), data analysis, and presentation
  • Understanding with Quality by Design approach to process development
  • Experience with commercial scale up, large-scale bio-manufacture and cGMP is a plus
  • Ability to independently design experiments, analyze complex data and interpret and presentexperimental results, required
  • Demonstrated leadership and critical thinking skill



  • While performing the duties of this job, the employee is frequently required to stand; sit; use hands to finger, handle, or feel; reach with hands and arms; and talk or hear.
  • The employee is occasionally required to walk; climb or balance; and stoop, kneel, crouch, or crawl.
  • The employee must frequently lift and/or move up to 10 pounds and occasionally lift and/or move up to 50 pounds.
  • Specific vision abilities required by this job include close vision, and ability to adjust focus.
  • In the performance of the duties of this job the employee is not required to travel
  • The employee will be required to communicate using telephone and e-mail
  • This will be a laboratory and office-based position that will require some non-standard working hours including early morning or later evening teleconferences to support global prospective and current clients


  • Phone reimbursement policy for qualified individuals
  • Free parking
  • Highly competitive healthcare with many plan options:
  • Medical (HMO/PPO/EPO)
    • Dental
    • vision
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Up to 10 weeks of 100% paid maternity leave
  • 2 weeks of 100% paid paternity, domestic partner, & adoption leave
  • Educational assistance program
  • 401k (traditional and Roth offered) with 100% match on first 5% deferred.
  • A suite of Arranta Bio paid insurance coverage, including life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • Employee Referral program
  • Competitive PTO plan, in addition to 10 company paid holidays (includes 2 floating holidays)