Scientist, Immune Regeneration

Location
Fort Lee, NJ
Posted
May 21, 2021
Hotbed
Pharm Country
Required Education
Masters Degree/MBA
Position Type
Full time

We're researching ways to regenerate the aged immune system. In a position with us focused on immue regeneration, you will get to develop engraftable human iPS cell-derived hematopoietic stem cells (iHSCs) and research ways to regenerate aged thymic organs.


With us, you'll get to:

  • Develop engraftment-competent human iHSCs
  • Design and execute independent research on iHSCs, examining quality control aspects of cell production, translational function and safety with emphasis on oncogenic landscape analyses and safety issues related to long-term engraftment
  • Derive and fully characterize different cell types from iHSCs, including designing assays to test their potentially improved function against aged HSCs
  • Devise and test practical, innovative strategies to rejuvenate the aging human immune system, including testing interventions to combat thymic involution


Please apply if you have:

  • PhD or another advanced degree in Immunology or another biomedical science field
  • Experience researching human hematopoietic stem cells and/or other aspects of immune regeneration
  • Experience with iPSCs and iHSC-derived cell types
  • Expert knowledge in experimental therapeutics and the therapeutic pipeline of primary HSCs and iHSCs, with an emphasis on practical, actionable interventions to treat and prevent age-related immune senescence and achieve immune regeneration/rejuvenation
  • Extensive experience in bench molecular and small molecule biology, cell biology, immunology, hematology, hematopoiesis and bone marrow niche biology


Ideally, you'll also have:

  • Expertise in and working knowledge of age-related immune senescence and hematologic dysfunction
  • General and working knowledge of aging biology, adult stem cells, regenerative and personalized medicine as well as gene therapy (AAV-mediated)
  • Experience with in vitro and in vivo models of immune-senescence and regeneration


And you'll need:

  • A friendly, easygoing personality
  • The ability to work in the United States without sponsorship

Salary

Starting base pay range: $130,000/yr - $170,000/yr


Starting additional compensation range: $7,500/yr - $17,500/yr

Starting position title and compensation are commensurate with experience.