R&D Specialist (Tumor Immunology)

Location
Tarrytown, New York, United States of America
Posted
May 21, 2021
Ref
24870BR
Required Education
Bachelors Degree
Position Type
Full time
The Immunology & Inflammation department is seeking a highly skilled and motivated R&D Specialist to contribute to the discovery and characterization of novel targets in cancer immunotherapy. The successful candidate will be a member of an innovative team utilizing cutting edge technologies to address outstanding questions in the field of cancer immunology and epigenetics. We are looking for someone who is passionate about scientific discoveries that will benefit cancer patients as well as individual growth and development.

As an R&D Specialist in Inflammation and Immunology, a typical day may include the following:

- Investigating molecular pathways involved in tumor immunity at the transcriptional and epigenetic level
- Establishing and executing epigenetic assays to understand the mechanisms of action of immunotherapy utilizing patient samples and humanized mouse models
- Performing tumor implantation in mice, tumor growth measurement, injections through various routes, general surgical techniques and collection of blood and tissue samples
- Tissue processing and purification of immune cells and in vitro cell based bioassay development (primary mouse and human cells)
- Investigating the components of the tumor microenvironment by multi-parameter flow cytometry
- Analyzing biological data using FlowJo and GraphPad Prism software
- Independently design, plan and execute experiments and maintain accurate electronic records
- Analyzing, interpreting and effectively communicating results during internal and external meetings; working in a fast-paced, result oriented research environment
- Collaborating proactively with team members to coordinate complex in vivo experiments, and with other departments to support cross-functional efforts
- Contribute to project advancement by developing new methods and models, and troubleshooting technical issues

This role may be for you if:

- You have excellent communication, organizational and time management skills are highly desired
- You have a collaborative spirit and ability to work in a fast-paced environment are necessary

To be considered for this role, you must have a BS or MS degree and 4+ years of experience in immuno-oncology lab research to join a highly interactive and innovative cancer immunology team. Proven experience with proper handling and care of mice, tumor implantation (syngeneic and xenogeneic tumor models), tumor growth measurement, injections through various routes, general surgical techniques and collection of blood and tissue samples is required. Experience with tissue processing, purification of immune cells and analysis with multi-parameter flow cytometry (FACS), and cell based bioassays is required Experience with epigenetic and chromatin-based assays is desired. We need someone who demonstrates hands-on experience with cellular and molecular biology techniques and independently designs and executes experiments, analyzes data, interprets results and presents data during internal and inter-departmental meetings. Proficient computer skills and experience collecting and analyzing biological data is a necessity. Required experience with Microsoft Office Excel, GraphPad Prism, and FlowJo.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.