Director Discovery Research (dc)

Redwood City, CA
May 18, 2021
Biotech Bay
Required Education
Associate Degree
Position Type
Full time
Adverum is looking for a Director of Discovery with strong leadership and communication skills to build and lead a team of highly skilled scientists overseeing the design and execution of studies to discover and develop novel, best-in-class AAV gene therapy technologies.

Working with our collaborators and inter-disciplinary colleagues, the individual will be responsible for discovery and translational efforts, including advancing existing research pipeline programs, and the proposal and initiation of new projects across a range of indications. The individual will also represent the Discovery Research team on cross-functional teams and regularly interface with internal and external colleagues to ensure timely and accurate dissemination of data. They will also work with the Business Development team to monitor the latest developments in gene therapy drug development and assist in diligence activities on opportunities for potential partnerships. The ideal candidate is a highly motivated and accomplished scientist with demonstrated experience in new target discovery and bringing candidates to IND.
What you'll do:
  • Build and manage a team of PhD scientists and research associates, provide scientific and strategic direction, technical oversight and efficient execution within the Discovery Research organization.
  • Successfully lead multiple discovery and translational research programs driving projects through key inflection points.
  • Identify key issues and allocate resources to support goals and progress of the pipeline.
  • Obtain in-depth knowledge of therapeutic concepts of interest and assist in setting priorities in the context of the external competitive landscape.
  • Provide expert opinions and develop effective group leadership within Adverum.
  • Participate in strategic pipeline building activities by providing scientific input.
  • Partner with Research, Preclinical and Analytical leadership to strategically direct platform enabling research.
  • Collaborate with colleagues within the organization and build partnerships with experts in the field.
  • Ability to write scientific manuscripts, review regulatory documents and represent Adverum at national and international gene therapy conferences.
  • Stay up to date on the literature and technical advancements to improve AAV gene therapy capabilities by identifying novel approaches and proposing experimental plans to test the hypotheses with the internal team and by the utilization of CROs.
  • Evaluate strategic external licensing opportunities and participate and due diligence when needed.
  • Contribute to a vibrant organizational culture that embraces curiosity, continuous learning, scientific rigor, professional development and collaboration.

About you:
  • Ph.D. in AAV Biology, Virology, Molecular Biology, Cell Biology or closely related discipline with at least 8 years of drug development experience in biopharmaceutical industry, with at least 5 years of people management experience
  • Deep understanding of cell and molecular biology methods, as well as histology and imaging techniques.
  • Effective communication and influencing skills with the proven ability to build, lead and develop a multidisciplinary team.
  • Must have experience in leading programs in early drug discovery to IND stages.
  • Track record of being a strategic leader and a key stakeholder for senior leaders across complex organizations.
  • Recognized leader in scientific specialty as evidenced by publications in leading peer reviewed journals.
  • Experience managing budgets and timelines for multiple projects
  • Exceptional verbal, presentation and written communication skills.
  • Excellent team player and mentor, with good interpersonal skills.
  • Experience in gene therapy, antibody development or AAV gene delivery platform development a plus.

About Us
Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.

At Adverum, Inclusion and Diversity are at our core. We believe in the power of being your authentic self.  We strive to create the space which allows for everyone in our Adverum Community to not only feel safe but encouraged to speak, learn from each other, grow in their professions and be the very best versions of themselves no matter what their age, ethnic background, gender, origin, religion or sexual orientation