Research Associate In-Vitro Pharmacology
Piper Companies is seeking a Research Associate In-Vitro Pharmacology in Philadelphia, PA to join a cell therapy leader committed to developing off-the-shelf cell therapies to expand patient access and provide an unparalleled opportunity to advance the course of cancer care.
The Research Associate/ Sr. Research Associate, In-Vitro Pharmacology will be part of company Research team and will be responsible for helping develop and optimize immune-assays to be used in the characterization of our iPSC derived cell products.
We are looking for a highly motivated and creative individual, with experience in cell culture, primary cell isolation and flow cytometry. The ideal candidate will work closely with scientists within the group and collaborate with members of various functional groups to help the company move product candidates into the clinic.
• Functional testing of iPSC derived cell products:
o Cytotoxicity assay (Incucyte / flow cytometry)
o Cytokine secretion (Multiplex-MSD / ELISA)
o Cell proliferation / persistence (flow cytometry)
• Tumor cell culture
• Isolation of PBMCs and purification of different immune cell types from peripheral/cord blood donors
• Phenotypic analysis of cell products by multi-color flow cytometry,
• Independent analysis and documentation of experimental data
• MS in biological sciences, with at least 2 years or a BS with 4 years of relevant experience working with immune cells, preferably T cells and NK cells
• Cell culture experience is essential
• Hands-on experience with multi-color flow cytometry, staining samples, running FACS instruments and interpreting data
• Experience running multicolor flow cytometry desirable
• Proven ability to perform various functional assays and learn new techniques rapidly
• Experience with functional assay development and optimization
• Ability to perform in a fast-paced environment and handle multiple priorities simultaneously
• Experience with the isolation of primary T-cells and NK cells from PBMCs is desired