Director, Formulation, CMC and Manufacturing

Vancouver, British Columbia (CA)
May 11, 2021
Required Education
Position Type
Full time

XYON Health Inc. (“XYON”) is a digital health company that plans to upend the men’s health and vitality market offering unique services and innovative consumer product offerings. XYON is at the leading edge of e-health and e-commerce having developed a high end brand and best-in-class topical formulation offerings. Our topical products are developed in partnership with leading formulation development and manufacturing firms world-wide. 

We are seeking a Director, Formulation, CMC and Manufacturing to join our team at an exciting stage.  You will be part of the founding team, joining seasoned experts and in a well-capitalized corporation. This is a permanent full-time, office or home office-based position.  The incumbent will be required to work flexibly across a number of development programs with an emphasis on sourcing, managing outsourced topical formulation development projects, outsourced cGMP drug product manufacturing and packaging campaigns and with contributions to intellectual property generation.



  • Manage, in whole and/or in part, concurrent CMC-related projects at XYON’s Contract Development and Manufacturing Organizations (CDMOs). These projects may include one or more of:

  • Pre-formulation and formulation development (for toxicology, clinical and/or commercial use)

  • Manufacturing process development

  • cGMP drug product manufacturing campaigns

  • Analytical method development and validation

  • ICH-compliant stability studies

  • Packaging, labeling and distribution

  • Perform CDMO contract-related activities (issuance of Requests for Proposal, negotiation, contract change control, performance monitoring, accepting deliverables, managing invoices and tracking accruals).

  • Draft the CMC (drug product) sections of any regulatory submissions (e.g. INDs, CTAs, NDAs).

  • Participate in CDMO audits and site visits as required.

  • Assist with formulation development activities with an emphasis on topical formulations.

  • Assist with managing intellectual property arising from formulation and manufacturing work.

  • Assist with the generation of dashboards for project reporting and development of summaries or slides for corporate presentations and board meetings.



  • A Ph.D. degree (or equivalent) in organic/physical organic/analytical chemistry, pharmaceutics, pharmacy or pharmaceutical sciences.

  • A minimum of 10 years experience in the pharmaceutical industry, directly related to formulation development and/or cGMP manufacturing preferably in small molecule drug products.

  • Experience with topical drug product development is a major asset.

  • Strong track record of successfully managing outsourced formulation development and manufacturing projects.

  • Good knowledge of modern formulation technologies, including those for modulating skin penetration, controlled release and reducing stability risks.

  • Good knowledge of project management methodologies and practices as pertinent to outsourced R&D and manufacturing (including management of risk, scope, budget and schedule).

  • Good knowledge and understanding of cGMP and of the US and Canadian regulatory environments.

  • Excellent written and oral communication skills, including the ability to communicate with scientific and non-scientific personnel.

  • Excellent attention to detail and commitment to providing accurate, high-quality work.

  • Good organizational and communication skills and the ability to manage multiple competing priorities.


To apply for this position, please e-mail your resume and cover letter and include “Director, Formulation, CMC and Manufacturing” in the subject line. All attachments must be saved as one file and be named: “Your Full Name – Director, CMC and Manufacturing.” We thank all applicants for their interest; however, due to the volume of applicants, only those chosen for interview will be contacted.