Director/Senior Director of Research Informatics

San Francisco, CA, United States
May 02, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Job Summary:

As Director of Research Informatics, you will serve in a highly visible role leading a team of Informatics Scientists to architect, implement, and support Research data management solutions that facilitate confident decision making. You will partner with your peers working onsite and remotely in Nurix's early drug discovery platform core areas, including Protein Sciences, DNA Encoded Chemistry and Screening, Medicinal Chemistry, Cellular Biology, and In Vivo Pharmacology to identify and solve unmet scientific data management needs. Together with Data Science, Software Development, and IT, the successful candidate will design, deliver, and support innovative solutions to increase scientific data findability, accessibility, interoperability, and reusability. The ability to both understand and solve the data needs of the Research organization are keys to success.

  • Lead a group of experienced bioinformatic and cheminformatic scientists to address the data science needs of the Research organization.
  • Partner with key Research stakeholders to design and develop tools to enable or improve chemical/assay data capture, search, visualization, and analysis processes.
  • Maintain and enhance existing databases and design and develop new databases to solve key needs.
  • Develop a Research application/tool map that defines product initiation, support, enhancements and/or upgrades, and retirement.
  • Identify technical training gaps and help develop strategies to improve user experience and gain performance benefit.
  • With regular prioritization from Executive Management, direct the portfolio of Research Informatics projects, maintaining alignment with Research goals and objectives.
  • Manage the Research application stack ensuring stability, compatibility, scalability, support, budget control, and license compliance.
  • Identify and champion new technologies, tools, and processes to improve the quality and speed of scientific decision-making.

  • BS/MS/PhD in Chemistry, BioChemistry, Biology, or a related field
  • Minimum 12 years' experience in Research Informatics.
  • Minimum 7 years' experience building teams and managing fulltime employees, consultants, and contractors
  • Minimum 10 years' hands-on experience with industry standard applications such as ChemCart, Dotmatics, ActivityBase, GeneData, Benchling, Sample Manager, LabWare, and/or LabVantage
  • Minimum 7 years' experience with budget planning and software vendor management
  • Excellent verbal and presentation skills in person and remote (phone/web)
  • Expertise writing business-appropriate emails, instant messages, and presentation materials
  • Expertise authoring requirements/specifications, workflow/process diagrams, and project plans
  • Expertise in MS Office (Excel, Word, PowerPoint, Visio)

Preferred Skills:
  • Minimum 7 years' experience working with data-analysis/pipelining/visualization tools and applications such as Pipeline Pilot, Knime, R/Shiny, Spotfire, and/or Tableau
  • Strong QA background
  • Experience working in validated/regulated systems


Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix's extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix's drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels.

Nurix's wholly owned pipeline comprises targeted protein degraders of Bruton's tyrosine kinase, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, an E3 ligase that regulates T cell activation. Nurix is headquartered in San Francisco, California.