Senior Scientist, in Vivo Pharmacology (Immuno-Oncology)

Location
Milpitas, CA
Posted
May 02, 2021
Ref
2533668
Required Education
Associate Degree
Position Type
Full time

Recursion is a clinical-stage biotechnology company decoding biology by integrating technological innovations across biology, chemistry, automation, data science and engineering to radically improve the lives of patients and industrialize drug discovery. Our team is working to solve some of the hardest, most meaningful problems facing human health today. Come join us in our mission to decode biology to radically improve lives, while doing the most impactful work of your life.

The Impact You’ll Make

  • Build drug discovery programs in diverse disease areas as in vivo lead on a cross-functional team of experts. Create relationships with CRO’s and help to lead our team of pharmacology scientists generate quality data you will then evaluate and interpret to facilitate program decisions.
  • Apply drug discovery principles in multiple programs in a range of disease areas.  Guide programs through lead-optimization, execution of a campaign of in vivo pharmacodynamic studies. Identify, optimize and validate efficacy models that demonstrate proof of concept in programs and aid in patient dose predictions.
  • Learn and show curiosity and openness to new tech in this role. You will work with data scientists and DMPK specialists to leverage PK/PD relationships and in vitro-in vivo extrapolations (IVIVE).
  • Collaborate with DMPK, chemists, biologists and data scientists to contribute to optimization through  compound selection and the identification of high-quality development candidates.

 

The Team You’ll Join 

This position reports directly to the Director of in vivo Pharmacology to help us expand our portfolio as we guide our programs toward the clinic. If you are passionate about discovering medicines, looking for the opportunity to build data and tools to accelerate drug-discovery, let’s talk.

***This position is based in Milpitas, CA.

 

The Experience You’ll Need

  • PhD in Biology, Pharmacology or a related life-science field
  • 4+ years of industry experience contributing preclinical efficacy data to project teams that enabled decisions
  • Understanding of small molecule drug discovery and applying PK/PD for optimization and selection of development candidates
  • In-depth, hands-on experience with animal models of human disease to demonstrate proof of efficacy. Proficiency generating and validating these animal models and assessing the translational aspects. Experience in immuno-oncology. Flow cytometry a plus!
  • Experience filing IND enabling documents. 
  • Excellent project, time management, problem solving skills and ability to work and lead in a cross-functional setting but also to coordinate and lead pharmacology research associates
  • Ability to articulate scientific data and strategic messages to internal partners and stakeholders
  • Explore scientific literature outside of one’s immediate area of expertise and apply this to problem solving
  • Experience selecting and managing CROs

 

The Benefits/Perks You’ll Enjoy

  • 100% Coverage of health, vision, and dental insurance premiums 
  • 401(k) with generous matching (immediate vesting)
  • Stock option grants
  • Two one-week paid company closures (summer and winter) 
  • Flexible vacation/sick leave
  • Generous paid parental leave (including adoptive)
  • Onsite daycare facility*
  • Commuter benefit and vehicle parking to ease your commute* 
  • Complimentary chef-prepared lunches and well-stocked snack bars* 
  • Monthly fitness/wellness stipend 
  • One-of-a-kind 100,000 square foot headquarters complete with a 70-foot climbing wall, showers, lockers, and bike parking*

*Subject to change for remote-based employees during the COVID-19 pandemic

 

More About Us 

Recursion is a clinical-stage biotechnology company decoding biology by integrating technological innovations across biology, chemistry, automation, data science, and engineering, with the goal of radically improving the lives of patients and industrializing drug discovery. Central to our mission is the Recursion Operating System, or Recursion OS, that combines an advanced infrastructure layer to generate what we believe is one of the world’s largest and fastest-growing proprietary biological and chemical datasets and the Recursion Map, a suite of custom software, algorithms, and machine learning tools that we use to explore foundational biology unconstrained by human bias and navigate to new biological insights which may accelerate our programs. We are a biotechnology company scaling more like a technology company. Recursion is proudly headquartered in Salt Lake City. 

Learn more at www.recursion.com, or connect on Twitter and LinkedIn.

Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status or any other characteristic protected under applicable federal, state, or local law.