Uniquely positioned to enhance quality of life in aging, at Alkahest, we are pioneering science that is rapidly being translated to the clinic. Our approaches utilize in vivo, in vitro, proteomic, and molecular techniques to identify new therapeutics and apply them to patients.
We are seeking a highly motivated and driven team member who will be key in advancing our immune-related scientific activities. Alkahest is developing therapies to address disorders of the central and peripheral nervous system that occur with aging, with a particular emphasis on disease where neuroinflammation is an important component. The selected candidate will use a combination of animal and human studies to assess the relationship of our drug candidates with immune mechanisms through techniques best suited for clinical translation. The role is critical in providing clinical tools to advance our therapeutic understandings of immune-related mechanisms and bridging the gap between preclinical and clinical findings. The role requires dedication, flexibility, excellent communication and organization, and will interact with teams from research, clinical and clinical operations departments to drive multiple projects in parallel.
Alkahest offers a competitive compensation and benefits package, opportunities for career growth and development, and a work environment that is collaborative, collegial, and fun.
Specific responsibilities include, but are not limited to:
- Designing, planning, and performing experiments using rodents in vivo and/or human samples
- Providing input on biomarkers that can be implemented in clinical trials to obtain human data
- Implementing, optimizing and performing immunological assays
- Multi-color flow cytometry
- Maintaining familiarity with current scientific literature
- Investigating and developing new methods and technologies for project advancement
- Identifying, managing and troubleshooting CROs and/or collaborators
- Writing scientific reports, contributing to IND filings, clinical protocols and other clinical and regulatory documents
- MS with 5 years industry and/or academic lab experience or PhD/MD with minimum of 2 years of progressively advancing industry and/or academic lab experience
- Experience in rodent and human immunology
- Experience with flow cytometry and other immune-related techniques
- Ability to work collaboratively and strong communication skills
- Attention to details and strong organizational skills
- Experience with CyTOF and other cutting edge immune tools is desired
- Experience with translational development is desired
- Experience with analysis of clinical trial samples is desired
- Experience with working with CROs is desired