Research Associate/Sr. Research Associate – Immunohistochemistry/Translational Science

Arcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies. We are an oncology-focused biopharmaceutical company leveraging its deep cross-discipline expertise to discover highly differentiated therapies and develop a broad portfolio of novel combinations addressing significant unmet needs.

We are located in the San Francisco bay area, in the heart of the world’s largest biotechnology research hub. Arcus Biosciences offers a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants. Arcus is an ambitious undertaking, and we fully expect our company to become a force in the discovery, development and commercialization of novel therapies for the treatment of cancer. Our employees enjoy operating in an exceptionally dynamic and cooperative environment in which the “rule book” has not yet been written.

Job Summary:

We have an opening in a newly formed Translational Science group for a Research Associate with experience in histology and immunohistochemistry (IHC) to support biomarker research for oncology therapeutic assets across all stages of clinical development.  The Research Associate will be responsible for tissue processing and embedding, microtomy/cryotomy (sectioning), routine IHC and histology stains, and microscopy/imaging. The role will also entail maintenance of histology laboratory equipment and organization of materials and reagents used for IHC. Candidates with a strong interest in histology, oncology, and pathology and desire to build expertise in this field are encouraged to apply. The successful applicant will have a proactive and collaborative work style, positive attitude, outstanding attention to detail and organization skills, as well as an interest in translational science and tissue diagnostics. 

Job Responsibilities:

The job duties and responsibilities for this Research Associate position include, but are not limited to:

• Performing established IHC assays on an automated platform and histology stains such as H&E
• Developing new IHC assays under the guidance of an IHC Scientist
• Sectioning FFPE or frozen blocks and mounting on microscope slides
• Processing and embedding tissues and cell pellets
• Constructing program-specific, custom tissue microarrays (TMAs)
• Imaging slides by brightfield and fluorescent microscopy or digital slide scanning
• Performing routine maintenance of histology laboratory equipment
• Maintaining sample and reagent inventories and databases, including digital slide archives
• Communicating and collaborating with team members and learning from senior staff

Qualifications:

The selected applicant will have a B.S. or B.A. with at least 2-5 years of relevant life science experience, including significant time in industry or extensive histology experience in an academic laboratory.  Alternatively, candidates with histotechnician/histotechnologist degrees and certification looking for experience in a fast-paced industrial environment will also be considered.  

Qualified applicants will be proficient in sectioning tissue for microscopic evaluation and have a working knowledge and hands-on experience with IHC techniques and microscopy (experience with automated staining platforms and digital image analysis methods is highly beneficial, but not required).