Research Associate

BridgeBio Gene Therapy, a subsidiary of BridgeBio Pharma, is focused on discovering and developing drugs for patients with grievous genetic diseases. We do this by:

Finding the right starting points to target diseases at their source.

Using a combination of a systematic assessment of the genetic disease landscape and informed diligence on the latest research, we find indications with clear mechanisms of pathogenesis that are ripe for translation into disease-modifying drugs.

Building products with world-class R&D personnel.

We employ industry-leading scientists that work closely with leading academics to prosecute a wide variety of drug programs at the highest level of scientific rigor. Our team combines biopharmaceutical veterans with up-and-coming leaders to drive entrepreneurial thinking grounded by experience.

BridgeBio finds, develops, and delivers breakthrough medicines for genetic diseases. The company bridges remarkable advancements in genetic science with the entrepreneurial engine required to rapidly create lifesaving medicines for patients with unmet needs. Founded in 2015 by a team of industry veterans, the company has built a portfolio of 20 transformative drugs ranging from pre-clinical to late-stage development in multiple therapeutic areas, including genetic dermatology, oncology, cardiology, neurology, endocrinology, renal disease, and ophthalmology. The company’s focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines. We have offices in San Francisco, Palo Alto, Boston, New York, and Raleigh with small satellites in other parts of the country.

To learn more, visit us at https://bridgebio.com

Who You Are:

The Research Associate will be responsible for laboratory activities to support BridgeBio’s growing gene therapy portfolio. The incumbent will report to a Research Scientist in our R&D group and work closely with other team members to develop and evaluate new therapeutic candidates in preclinical models. This is a hands-on research position in our Raleigh, NC laboratory and a great way to join a small team doing fantastic work.

Responsibilities:

• Develop and perform molecular biological assays on an automated liquid handler
• Perform routine experiments: DNA/RNA/protein isolation, qPCR, ddPCR, ELISA, etc.
• Assist with data acquisition and data analysis
• Maintain associated laboratory equipment and plan routine maintenance and quality controls
• Assist with assay development and transfer for qualification/validation at contracted vendors
• Support writing of work instructions, SOPs, and reports

Education, Experience & Skills Requirements:

• BS/MS with 2-5 years of experience
• Previous automation experience is required
• Experience with automated laboratory instrumentation such as liquid handlers
• Strong working knowledge of nucleic acid purification and qPCR is preferred
• Experience with Eppendorf epMotion automated liquid handler will be an advantage
• Must be able to accurately document and archive data; Attention to detail and adherence to protocols are expected
• Strong interpersonal skills, good problem-solving skills, and effective written and oral communication are necessary
• Gene therapy experience is a plus

What We Offer:

• Patient Days, where we are fortunate enough to learn more about the lives we are looking to impact and a real exchange of ideas as to how we can improve our efforts
• A culture inspired by our values: put patients first; think independently, be radically transparent; every minute counts, and let the science speak
• Learning and development training to help employees be the best version of themselves
• Collaborative business environment
• Excellent compensation package (Base, Performance Bonus, Stock, RSU programs)
• Excellent benefits package
• Flexible PTO
• With office locations in San Francisco, Boston, New York, and Raleigh, there are ample cross-collaboration opportunities with other BridgeBio Pharma programs
• A fast-paced, data-driven, work environment with world-class R&D minds and capabilities
• Work with the most productive groups of R&D operators in the industry
• Partnerships with leading institutions
• A platform for meaningful scientific contributions to shine
• Commitment to Diversity & Inclusion – with initiatives like Women at Bridge, we are committed to fostering an inclusive environment where every person feels respected for who they are, empowered to contribute, inspired to lead, and supported in their efforts to do so

We will not accept unsolicited resumes from agencies. Please do not send agency resumes to our website or BridgeBio and affiliating employees.