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Principal Mechanical Engineer

Employer
Mammoth Biosciences
Location
Brisbane, CA, United States
Start date
Apr 21, 2021

View more

Discipline
Engineering, Mechanical/Manufacturing Engineer
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

COMPANY

Mammoth Biosciences, Inc. is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. By leveraging its internal research and development and exclusive licensing to patents related to Cas12, Cas13, Cas14 and CasPhi, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Mammoth is democratizing disease detection with easy and affordable point-of-care tests that allow real-time and simultaneous detection of multiple conditions, along with high-throughput tests that allow for unprecedented testing volume. Further, the company is transforming disease treatment with its proprietary micro-sized CRISPR proteins that enable new editing and delivery options. Based in Brisbane, CA, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Prize winner Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Decheng, Mayfield, NFX, and 8VC, and leading individual investors including Brook Byers, Tim Cook, Bob Nelsen, and Jeff Huber.

OPPORTUNITY

Mammoth is seeking a Principal Mechanical Engineer with expertise in instrumentation and consumable designs. You will work in a diverse, dynamic, multifunctional team to package our novel CRISPR enzymes into a molecular diagnostics system. The successful candidate will have experience in bringing products from concept to production. The position will require creativity and outside-of-the-box thinking with strong technical and analytical skills.

KEY RESPONSIBILITIES
    • Manage all aspects of mechanical engineering projects from concept through detailed design, prototyping, and verification/validation testing
    • Design electromechanical subsystems involving fluidics, microfluidics, thermal cycling, and optics
    • Perform engineering calculations and simulations as necessary to support design decisions
    • Review and provide feedback on mechanical designs from external engineering teams
    • Transfer product from development to manufacturing
    • Estimate costs, timelines, and budgets for new designs
    • Manage Solidworks and PDM


REQUIRED QUALIFICATIONS
    • Bachelor's degree in an engineering-related discipline
    • 10 years of professional mechanical engineering experience
    • Extensive experience with SolidWorks
    • Experience with FEA analysis of mechanical components (thermal, stress, fluidics)
    • Demonstrated experience designing, prototyping, and testing mechanical assemblies
    • Proficiency with GD&T and tolerance analysis


PREFERRED QUALIFICATIONS
    • Experience working in the medical device industry
    • Basic project management skills and ability to hold to a project timeline
    • PDM administrative experience
    • Electromechanical and fluidics experience
    • Ability to function in a fast-paced small company environment with minimal direction and ability to adjust workload based upon changing priorities
    • Ability to think critically with demonstrated troubleshooting and problem-solving skills
    • Excellent interpersonal, verbal, and written communication skills


BENEFITS
    • Company-paid health/vision/dental benefits
    • Unlimited vacation and generous sick time
    • Company-sponsored meals and snacks
    • Wellness, caregiver and ergonomics benefits
    • 401(k) with company matching


It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.

Company

Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.

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Company info
Website
Phone
(650) 294-8583
Location
South San Francisco
CA
94080
United States

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