Bioinformatics Data Engineer / Senior Bioinformatics Data Engineer

Menlo Park, CA, United States
Apr 21, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit

The Data Science and Biostatistics organization is looking to hire a Bioinformatics Data Engineer (BXDE) to partner with computational, engineering and clinical study teams in developing data solutions for the GRAIL product pipeline.

The BXDE will collaborate with software engineers and scientists to develop and produce analysis-ready datasets for clinical research and product development. In order to understand analysis dataset requirements, the BXDE will read laboratory protocols, Statistical Analysis Plans, and other analysis planning documents in addition to meeting with scientists, biostatisticians, and other partners.

The BXDE will become proficient in GRAIL's analysis system architecture, including primarily GRAIL's LIMS for laboratory data; Electronic Data Capture (EDC) for clinical study data; the Bioinformatics Pipeline for sequence analysis and cancer classification data; and TidyData, the system that aggregates, packages, and serves datasets crafted from LIMS, EDC, and Pipeline outputs.

The BXDE will develop code and procedures to support dataset generation, perform QC, and solve issues that arise during dataset generation. The BXDE will also collect requirements, develop prototypes, and collaborate on production implementations of new reporting-related features as needed.

Additionally, the BXDE may have opportunities to collaborate on statistical analyses and creation of analysis reports and interactive data visualizations.

You Will:

• Develop and support processes for analysis dataset creation, QC, and release
• Develop standards and procedures to improve efficiency of new dataset implementation
• Collect user requirements and develop custom reporting features as well as prototypes for future production reporting features
• Define dataset QC procedures, report templates, and automated reports for streamlined execution of QC procedures
• Maintain data integrity and quality throughout the data lifecycle, including ensuring clinical study-related blinding where appropriate

Your Background Includes:

• BS or MS in a scientific field (life science, computer science, engineering, mathematics, statistics, bioinformatics, etc.)
• Experience with R or Python programming is required
• Experience with basic concepts of molecular biology is required
• Experience with cross-functional collaboration while ensuring data quality and commitment to analysis reproducibility is required
• Excellent interpersonal communication (written and verbal) and organizational skills is required
• Excellent team player with a demonstrated track record of success in a cross-functional team environment. Consistent commitment to delivering on team goals with a sense of shared urgency is required
• Experience in the field of molecular diagnostics is a plus
• Experience with CDISC data models is a plus
• Experience with Amazon Web Services is a plus
• Experience with data visualization and analytics tools is a plus

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

GRAIL, Inc. and its affiliates and subsidiaries ("GRAIL") does not accept any liability for fees for resumes from recruiters or employment agencies ("Agency"), without a binding, written recruitment agreement between GRAIL and Agency describing the services and specific job openings ("Agreement"). GRAIL may consider any candidate for whom an Agency has submitted an unsolicited resume and explicitly reserves the right to hire those candidate(s) without any financial obligation to the Agency, unless an Agreement is in place. Any email or verbal contacts with any person within GRAIL is inadequate to create a binding agreement. Agencies without an Agreement are requested not to contact any hiring managers of GRAIL with recruiting inquiries or resumes. Agencies interested in partnering with GRAIL may contact GRAIL's HR Department through our Customer Service team .