Research Associate, Protein Sciences (Fermentation)

Company Description:

Molecular Templates is a clinical-stage biopharmaceutical company focused on the discovery and development of differentiated, targeted, biologic therapeutics. Our proprietary biologic drug platform technology, known as engineered toxin bodies, or ETBs, leverages the resident biology of a genetically engineered form of Shiga-like Toxin A subunit to create novel therapies with potent and differentiated mechanisms of action for cancer and other serious diseases. MTEM currently has multiple clinical-stage ETB candidates in development including MT-5111, TAK-169, and MT-6402. Additional preclinical compounds derived from our ETB platform technology are being advanced toward clinical development. Additional information about Molecular Templates can be obtained at www.mtem.com.

Position Overview:

The Research Associate (RA) is an integral member of the research and development (R&D) team and will be involved in ETB protein production and analysis. This is a laboratory-based position in a team setting. The RA will be responsible for conducting protein production and analysis tasks based on established protocols with all work being documented. Responsibilities may change in line with prioritization at the discretion of the management team.

Job Responsibilities will include:

• Performs research and/or development in collaboration with others for projects.
• Makes detailed observations, analyzes data and interprets results.
• Maintains a high level of professional expertise through familiarity with internal training and scientific literature, as appropriate for the level of work assigned.
• Presents data and methods in R&D meetings, as needed and assigned.
• Produces and purifies ETB proteins in an E. coli- based expression system according to established protocols.
• Conducts analytical protein assays according to established protocols.
• Accurately documents all tasks in a timely manner.
• Assists in the design and execution of new experiments or test protocols as needed under the direction of management.
• Performs general lab maintenance including equipment upkeep, lab cleanliness and organization and solution/reagent preparation.
• Other tasks, including independent projects, as needed.

Qualifications:

• A bachelor's degree in a life science, biochemistry, biomedical engineering or related field is strongly preferred.
• Previous lab-based experience (academic or industry) is preferred.
• Ability to work on problems and projects of limited scope (defined by management).
• Demonstrated ability to safely follow detailed directions and protocols in a laboratory environment.
• Relevant experience in a laboratory setting involving molecular biology and recombinant protein expression from a prokaryotic (E. coli) system is required.
• Experience in molecular biology techniques, required.
• Experience in operating bioreactor systems for microbial fermentation is highly desired
• Experience in operating AKTA FPLC system for protein purification is desired.
• Experience conducting analytical protein assays (i.e. A280 and SDS-PAGE) is required.
• Ability to work in a fast-paced, team environment.
• Ability to build stable working relationships with team members.
• Strong time-management skills.
• Strong written and verbal communication skills.
• Computer skills with knowledge of spreadsheet and word processing software.
• Ability to lift to a height of 4 feet, items weighing up to 60 lbs, on a regular basis.

Reporting Structure:

This position reports to R&D management. This can vary in level depending on the specific assignments.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc https://mtem.isolvedhire.com