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Research Associate II/III

Employer
Sangamo Therapeutics, Inc.
Location
Brisbane, CA
Start date
Apr 19, 2021

View more

Discipline
Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

Manager: Scientist II, BioAnalytical Sciences
Department:  Preclinical Development
Location: Brisbane, CA

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. At Sangamo, we are passionate in developing genomic medicines to transform the lives of patients with serious diseases. We transform lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Sangamo is a company where individuals can flourish, grow and develop their expertise.

We are seeking top talent to join our team. Let’s build a better future together.

JOB SUMMARY:   
The Research Associate II/III will participate in development, qualification, and implementation of bioanalytical methods, with a focus on methods for immunogenicity assessment and biomarker analysis, in support of Sangamo’s exciting genomic medicines programs. This individual will work closely and collaboratively with colleagues and senior leaders to progress Sangamo’s preclinical and clinical programs. The position requires adaptability, excellent planning, strong organization and communication skills, as well as the ability to work independently in a fast-paced, team-oriented environment.

ESSENTIAL FUNCTIONS:

  • Participate in development and qualification of bioanalytical methods for preclinical and clinical studies. Troubleshoot and optimize bioanalytical methods. Support bioanalytical method transfer to CRO.
  • Conduct sample analysis according to established protocols. Plan bioanalytical runs and work closely with sample management group.
  • Record observations in detail. Analyze and summarize assay data. Present bioanalytical results expeditiously to project team and/or other groups.
  • Generate SOPs, method qualification plans, method qualification reports, study phase bioanalytical reports, and other related documents for review by senior staff. Maintain well-organized laboratory notebooks following good documentation practices.
  • Stay current with respect to new and relevant technologies through scientific literature. Evaluate innovative bioanalytical technologies and methodologies to solve challenging bioanalytical problems.
  • May serve as bioanalytical representative at project team meetings.
  • Participate in internal or external scientific meetings and conferences.


EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

  • 2 – 5 years of relevant industry experience in biotechnology or pharmaceutical companies
  • Hands-on experience in anti-drug antibody (ADA), enzyme / cell-based / non-cell based neutralizing antibody (NAb) assays utilizing ELISA, MSD, FACS, etc. Demonstrated ability to troubleshoot bioanalytical methods and produce creative solutions. Experience with biomarker assays is a strong plus.
  • Hands-on experience in anti-drug antibody (ADA), enzyme / cell-based / non-cell based neutralizing antibody (NAb) assays utilizing ELISA, MSD, FACS, etc. Demonstrated ability to troubleshoot bioanalytical methods and produce creative solutions. Experience with biomarker assays is a strong plus.
  • Good understanding of regulatory guidance and industry white papers relevant to ligand-binding assays, immunogenicity assessment, and large-molecule bioanalytical methods.
  • Knowledge of Microsoft Office Suite and other relevant data analysis software (SoftMax® Pro, JMP, GraphPad Prism, etc.).
  • Ability to work independently in a team-oriented environment with minimal supervision. Strong written and oral communications skills. Highly motivated with strong work ethics.



Sangamo is an equal opportunity employer

The above reflects management’s definition of essential functions for this position but does not restrict the tasks that may be assigned.The above duties are representative only; management may assign or reassign duties and responsibilities to this position at any time.

 


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Company

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. At Sangamo, we are passionate in developing genomic medicines to transform the lives of patients with serious diseases. We transform lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise.

We are seeking top talent to join our mission. Let’s build a better future together.

Stock Symbol: SGMO

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Company info
Website
Phone
(510) 970-6000
Location
7000 Marina Blvd
Brisbane
CA
94005
United States

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