Research Associate, Gene-Based Assays

Location
South San Francisco, CA, United States
Posted
Apr 16, 2021
Ref
5044597002
Required Education
Other
Position Type
Full time
JOB PURPOSE

Sana Biotechnology is looking to expand our team with creative and highly motivated individuals who believe in the potential of cells as engineered medicines, have the vision to do creative things, and the determination to execute that vision.

We are looking for a qualified research associate to help build the Analytical Development department at Sana Biotechnology. This person will join an innovative, multi-disciplinary team developing and implementing analytical methods and data analysis to support the advancement of Sana's pipeline. This position will work cross-functionally with scientists from Research, Process Development, and Quality Control to determine the appropriate methodologies to assess drug products, intermediates, and critical reagents. This is a unique opportunity to develop assays to characterize the functional attributes of gene and cell therapy products.

DUTIES AND RESPONSIBILITIES
  • Support the development of robust analytical methods for cell and gene therapy products, critical reagents and raw materials
  • Perform routine testing to support process development
  • Prepare test procedures, protocols and other technical documents
  • Identify and troubleshoot unusual results or instrumentation issues
  • Transfer methods to quality control and support their implementation and execution
  • Characterize gene and cell therapy products for regulatory filings and to demonstrate comparability between lots
  • Purchase and maintain analytical instrumentation and coordinate support with vendors
  • Occasional travel between Sana locations

QUALIFICATIONS

Basic Qualifications
  • BS degree in microbiology, virology, biology, biochemistry, molecular biology or other life science with 1+ years of industry experience in analytical development, quality control or process development roles, or relevant research in an academic setting
  • Experience with molecular biology techniques including nucleic acid purification, qPCR, and/or ddPCR
  • Detailed record keeping and documentation of relevant experimental details
  • Excellent written and verbal communication skills
  • Ability to design thoughtful experiments, critically evaluate data, and summarize results in a meaningful way
  • Must be resourceful with respect to learning new skills, techniques, and therapeutic modalities
  • Ability to work in a high paced team environment, meet deadlines, and prioritize work from multiple projects

Preferred Qualifications
  • Experience with eukaryotic cell culture and aseptic technique
  • Previous experience with automation, plate-based assays, and/or ELISAs
  • Familiarity with various software packages used for data analysis