Research Associate / Senior Research Associate, Functional Genomics (Contract)

South San Francisco, CA, United States
Apr 14, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Position Summary:

We are seeking a talented and highly motivated Research Associate with cell line engineering experience to join our functional genomics team. These individuals will collaborate closely with colleagues from our therapeutic area teams to develop design and build engineered cell lines and develop assays using a variety of readout technologies, execute screens, and follow-up hits. These individuals will also help establish our laboratories and the infrastructure for screening operations in collaborations with colleagues in our research infrastructure and data science teams. This person will support functional genomics scientists in genome screens such as CRISPR, and will do cellular work in support of new screenings.

Education and Experience:

Candidates for these positions should have a BS/MS in a biological science discipline and at least 2 years of relevant experience in a pharmaceutical, biotechnology, or 5 years in an academic setting. Ideal candidates will have a depth of experience in molecular biology and cell-line engineering experience

Required Skills:
  • Broad laboratory experience and skills in molecular and cell biology is required.
  • Expertise with mammalian cell culture is required, and Next Gen Sequencing methodologies is preferred.
  • Experience with cell line engineering using random integration and lentivirus transduction is required. Expertise in cell line engineering via CRISPR is preferred.
  • Expertise in single cell cloning via limiting dilution and in using flow sorting to generate stable cell pools is required.
  • Experience in gDNA and RNA isolation, RT-PCR, and NGS library generation is preferred.
  • Excellent data analysis skills and experience with a variety of scientific software applications is required. Successful candidates will also have strong experimental design and troubleshooting skills.
  • Excellent communication, presentation, collaboration, time-management, and organizational skills and are required.
  • The successful candidates will be ambitious and energetic self-starters, be motivated to apply their skills and creativity to target and drug discovery, and enjoy working in a fast-paced team environment.