Research Lab Specialist II
The Lawrence J. Ellison Institute for Transformative Medicine strives to leverage technology, spark innovation, and drive interdisciplinary evidence-based research to reimagine and redefine cancer treatment, enhance health, and transform lives. Under the visionary leadership of David B. Agus, MD, The Ellison Institute was designed to tackle the difficult questions in health care and research to push the boundaries of medicine forward. To accomplish this, the Institute offers multifaceted programs, including a cancer center, cross-disciplinary research laboratories, a health policy think-tank, and community outreach and educational opportunities. Please visit http://ellison.usc.edu to learn more about The Ellison Institute and our brand new, state-of-the-art facility in West Los Angeles.
The Lawrence J. Ellison Institute is seeking a talented and passionate Research Lab Specialist II to join its team. As part of the Ellison Institute, the Mumenthaler lab is focused on evaluating the role of the tumor microenvironment in cancer progression. Our team is a diverse group of innovative and talented professionals who use organs-on-chips as a cutting-edge technology to investigate mechanisms of colorectal cancer disease progression and evaluate potential treatment approaches. As part of the Mumenthaler lab, the candidate will perform advanced tissue culture techniques, working with 3D organoids and a microfluidic organ-on-chip platform, to establish a patient-specific colorectal cancer chip. The candidate will perform various techniques, including imaging, immunostaining and ELISAs, to validate the tissue structure and function of the model is physiologically relevant. The candidate will work closely with the Ellison Institute’s Cell Line Team, who has developed and characterized a biobank of patient-derived organoids, and the Biomimetic Models Team, who has established organs-on-chip platforms, to carry-out the proposed tasks. This work will provide the basis for a personalized chip platform for patients with colorectal cancer so that the pathogenic mechanisms related to specific tissue elements can be elucidated and potential therapies evaluated.
The Research Lab Specialist II is responsible for performing 3D cell culture, imaging, immunostaining, and ELISAs. They will also prepare technical reports, develop protocols, and perform quantitative analyses.
- Design and documentation of experiments
- Detailed record-keeping and assembly of timely reports
- Weekly presentations to supervisory staff
- Effective written and oral communication skills
- Works collaboratively
Excellent verbal and communication skills, and the ability to work both independently and in a team environment are required. Key success factors in the performance of this position include attention to detail, the ability to collaborate across disciplines, and curiosity.
Preferred Education: MS degree
Preferred Experience: Advanced mammalian tissue culture techniques, live cell microscopy
Preferred Field of Expertise: Molecular/cellular biology, biomedical engineering or other relevant discipline.
Salary: 80k -100k