Senior Research Associate / Research Associate, Process Development

Location
San Diego, CA, United States
Posted
Apr 07, 2021
Ref
473AFP
Hotbed
Biotech Beach
Required Education
Bachelors Degree
Position Type
Full time
Fate Therapeutics is seeking a motivated, conscientious, and talented cell biologist to support the company's process development group, pursuing the derivation of natural killer (NK) and iT cells from induced pluripotent stem cells (iPSCs) for use in cell therapy applications. The successful candidate will support experiments involving iPSC maintenance and expansion, in vitro differentiation of iPSCs towards the hematopoietic lineages, and further differentiation and expansion of NK and T cells. Candidates must have cell culture experience; knowledge of stem cell biology, the hematopoietic system, and immunology is preferred. This position will require independent research and coordination with the process development group. This full-time position reports to a Process Development Scientist, requires dedicated weekend hours, and is located at our corporate headquarters in San Diego, CA.

Responsibilities:
• Perform assessment of cell cultures, maintenance of iPSCs, hematopoietic differentiations, and NK and T cell differentiations
• Expansion and seeding of feeder cells
• Reagent management and aseptic preparation of reagent stocks including media, cytokines, & small molecules
• Detailed record-keeping of all activities in accordance with good documentation practices
• Communication of culture assessments, results, and reagent inventories in a timely manner to relevant team members

Qualifications
• B.S./M.S. plus a minimum of 2 years of relevant experience in cell culture techniques
• Meticulous record-keeping skills and excellent communication skills are a must
• Working knowledge of stem cell biology, immune system and/or developmental hematopoiesis is preferred
• Prior flow cytometry data acquisition and analysis experience is a plus
• Strong attention to detail, analytical, time management, organizational and interpersonal skills
• Prior industrial cGMP experience and/or process development experience is a plus

Working Conditions and Physical Requirements
• Dedicated weekend work (8 hours, Saturday, or Sunday) will be required with one dedicated day off during the workweek
• Will require working with cell lines of human and/or animal origin
• 100% on-site work at corporate headquarters in San Diego, CA The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time.

For consideration send cover letter and resume to: careers@fatetherapeutics.com and reference job 473AFP.

About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for patients with cancer. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company's immuno-oncology pipeline includes off-the-shelf, iPSC-derived natural killer (NK) cell and T-cell product candidates, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens using chimeric antigen receptors (CARs). The Company's pipeline also includes ProTmune™, a pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial for the prevention of graft-versus-host disease in patients with hematologic malignancies undergoing allogeneic stem cell transplant. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.