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Scientific Associate II (Purification)

Employer
CSL Behring
Location
Holly Springs, North Carolina
Start date
Apr 6, 2021

Job Details

About CSL

With operations in 35+ nations and ~27,000 employees worldwide, CSL is driven to develop and deliver a broad range of lifesaving therapies to treat disorders such as hemophilia and primary immune deficiencies, and vaccines to prevent influenza. Our therapies are also used in cardiac surgery, organ transplantation and burn treatment.

CSL is the parent company of CSL Behring and Seqirus. CSL Behring is a global leader in the protein biotherapeutics industry, focused on bringing to market biotherapies used to treat serious and often rare conditions. CSL Behring operates CSL Plasma, one of the world's largest collectors of human plasma, which is used to create CSL's therapies. Seqirus is one of the largest influenza vaccine companies in the world and is a transcontinental partner in pandemic preparedness and a major contributor to the prevention and control of influenza globally.

We invite you to take a look at the many career possibilities available around the globe and consider building your promising future at CSL by becoming a member of our team!

Job Description

Job Purpose

The person in this role will support TD downstream projects including developing, defining, and implementing purification processes, driving continuous improvements, and providing commercial support for multiple influenza vaccine platforms.

Major Accountabilities

 

  • Partner with diverse team members from various functions, countries and members at various levels in the organization.
  • Solve complex problems using analytical thinking gained through formal education and/or previous roles.
  • Both independently and collaboratively design and execute small scale experiments to characterize and define bioprocess steps.
  • Independently develop, troubleshoot, and scale up in vitro nucleic acid synthesis.
  • Generate test article material for Toxicology studies (GLP) and Phase I clinical studies (GMP).
  • Independently operate small scale bioprocess equipment including TFF, NFF, centrifugation.
  • Provides on-going support on projects of varying size often under tight deadlines, including guidance to others as needed, applying knowledge of broader project objectives to provide input that furthers project success.
  • Understand and interpret experimental data and results to support decisions and definition / knowledge of purification processes.
  • Understand and apply bioprocess scale-up principles and strategies.
  • Prepare technology development study protocols and reports in support of process development, transfer and regulatory documents
  • Communicate (presentations, write-up in technical documents, etc.) results to colleagues, project teams, management and external partners.
  • Be accountable for developing own self to enhance contribution.
  • Function effectively as a core team member.

 


Minimum Qualifications:

 

 

 

  • Bachelor's Degree in related scientific or engineering field required; Bachelor's Degree in Biochemistry or Molecular Biology preferred..
  • Molecular Biology and Biochemistry background preferred.
  • Minimum of 3 years of related experience or Master's Degree in related scientific field with 0 years related experience
  • Knowledge and experience handling nucleic acids required
  • Knowledge of aseptic technique required
  • Experience with lab/pilot scale TFF systems is desired
  • Working knowledge of GLP/GMP is desired
  • Knowledge of bioprocess unit operations, especially in vitro nucleic acid synthesis, as well as centrifugation, precipitation, TFF and NFF filtration, and engineering scaling principles, is desired
  • Understanding/experience with protein biochemistry is a plus
  • Knowledge of and experience in application of statistical techniques such as Design of Experiments (DOE) is a plus
  • Demonstrated knowledge of / expertise with analytical methods (e.g. SDS PAGE, Western Blot, HPLC, ELISA, Picogreen) is a plus
  • Ability to work with cross functional teams is required
  • Strong communication skills, technical writing ability, and good attention to detail is required
  • Must be a self-starter and able to work with minimal supervision

 

Company

As the third largest global biotechnology company with employees in more than 35 countries, CSL Behring is focused on serving patients with serious and rare diseases, including coagulation disorders, primary immune deficiencies, hereditary angioedema, respiratory disease and neurological disorders. We collaborate with patient and biomedical communities to improve access to therapies, advance scientific knowledge and support future medical research. 


CSL Behring's dynamic environment fosters innovation and attracts the best and brightest who share a commitment to helping save lives. People here are free to live their Promising FUTURES where they can fulfill their individual career aspirations and realize their potential. 


CSL Behring is committed to diversity and inclusion, both of which underpin our Values of patient focus, innovation, collaboration, integrity and superior performance. We believe that by harnessing and honoring the unique capabilities, experiences and perspectives of our people, we are better able to serve our patients.


CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. The parent company, CSL Limited, headquartered in Melbourne, Australia, employs more than 27,000 people, and provides its life-saving medicines in more than 70 countries. 
For more information visit www.cslbehring.com. Help us deliver on our promise to save lives and protect the health of people around the world. Promising FUTURES start at CSL Behring!

Stock Symbol: CSL

Stock Exchange: Australian Securities Exchange

Company info
Phone
610-878-4000
Location
1020 First Avenue
King of Prussia
Pennsylvania
19406
United States

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