Scientist, Cancer Immunotherapy
- Employer
- Fate Therapeutics
- Location
- San Diego, CA, United States
- Start date
- Apr 3, 2021
View more
- Discipline
- Science/R&D, Biotechnology, Immunology, Oncology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Beach
Job Details
• Investigate, develop, and employ novel strategies to enhance T cell function for the next generation
iPSC-derived T cells
• Differentiate and characterize off-the-shelf, iPSC-derived T cells
• Conduct routine and develop immune cell phenotypic analysis with flow cytometry and RNAseq
• Design and execute experiments to investigate function of CAR-T cells derived from iPSC, including in
vitro tumor killing and real time immune cell analysis for in vitro killing and persistence
• Oversee and execute in vivo experiments with support from the in vivo pharmacology group
• Deliver/present results in a multidisciplinary team environment that includes collaborations with top
research laboratories and institutes
Requirements
• PhD degree in Cancer Biology, Immunology, Cell Biology or related fields with 0-2 years of relevant
experience
• Prior experience with multi-color flow cytometry and data analysis
• Experience with 8+ color flow cytometry is a plus
• Experience with tumor microenvironment analysis is a plus
• Experience with transfecting primary immune cells including retroviral/lentiviral transduction is a plus
• Excellent written and oral communication, organization, as well as data analysis skills
Working Conditions and Physical Requirements
• 100% on-site work at corporate headquarters in San Diego, CA.
• Occasional evening and weekend work will be necessary
• Will require working with cells and cell lines of human and/or animal origin
The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. For consideration send cover letter and curriculum vitae to: careers@fatetherapeutics.com and reference job 455WY.
About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for cancer and immune disorders. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company's immuno-oncology product candidates include natural killer (NK) cell and T-cell cancer immunotherapies, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens with chimeric antigen receptors (CARs). The Company's immuno-regulatory product candidates include ProTmune™, a pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial for the prevention of graft -versus-host disease, and a myeloid-derived suppressor cell immunotherapy for promoting immune tolerance in patients with immune disorders. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.
Company
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune disorders. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s effector cell pipeline includes multiplexed-engineered, iPSC-derived natural killer (NK) cell and T-cell product candidates, which incorporate novel synthetic controls of cell function, such as chimeric antigen receptors (CARs) to target tumor-associated antigens and are intended to deliver multiple mechanisms of therapeutic importance to patients including in combination with well-established cancer therapies. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.
- Website
- http://www.fatetherapeutics.com/
- Phone
- 858.875.1800
- Location
-
12278 Scripps Summit Drive
San Diego
California
92131
United States
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