Senior Scientist, Antibody Discovery

San Francisco, CA, United States
Apr 03, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
We are looking for a highly motivated, technically savvy Senior Scientist to join the antibody discovery group at Zai Lab US in Menlo Park, CA. This is an exciting opportunity to join the growing antibody discovery team and make a significant impact to expand antibody discovery capabilities. In this role the successful candidate is expected to improve and champion a single B cell cloning platform to strengthen the discovery of high-quality lead antibody molecules. The successful candidate must possess a combination of strong technical, communication and interpersonal skills to work effectively with a diverse team across a broad range of biological targets and therapeutic areas.

This position is located in Menlo Park, CA.

- Contribute to the development and optimization of an existing single B cell platform within the Antibody Generation department
- Fully integrate the single B cell cloning protocol into lead generation workflow
- Innovatively approach single B cell capture and antibody genes preservation along with antibody function evaluation and characterization
- Stay informed about related novel technologies and contribute to the vision of the technology development especially in the space of immune cell biology and single cell analytics

- Ph.D. in immunology or related discipline, and 2+ years of experience industry experience OR
- MS with 8+ years of experience in immunology or related discipline
- In-depth knowledge of B/T cell biology and humoral and cell mediated immune responses
- Hands on experience in FACS using BD and/or Sony systems, target-centric B cell sorting or selection experience
- Experience in sorting strategies multi-parameter fluorescent flow cytometry panels design
- Knowledge of protein purification, fluorescent probes generation and biochemical protein characterization
- Strong hands-on experience with single B cell antibody cloning and antibody expression
- Proficiency in cell biology techniques including cell culture
- Highly technical knowledge of molecular biology techniques
- Highly innovative and self-motivated
- Excellent time management and organizational skills
- Demonstrated ability to work in a fast pace environment as a member of a multidisciplinary team

Preferred Qualifications:
- 5+ industry experience
- NGS experience
- Experience developing therapeutics against membrane targets including GPCRs

If you are interested in this position, please send an email with your resume to