Senior Scientist

Cambridge, MA, United States
Mar 29, 2021
Required Education
Position Type
Full time
Why Join Intellia?

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just treat people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.


Intellia Therapeutics is seeking an experienced Senior Scientist to join the RNA Chemistry Team, which is responsible for the production of synthetic oligonucleotides. This individual will be involved in a complete production process for the identification, implementation & fulfillment of synthesis, purification and reaction scheme analytical characterization and method development of oligonucleotides.

  • Be the key go-to person with strong hands-on experience and detailed knowledge of oligonucleotides.
  • Execute synthesis, deprotection, purification, & downstream processing of oligonucleotides.
  • Operate, maintain & calibrate synthesis platforms and other scientific equipment.
  • Design & implement semi-preparative, analytical HPLC and LC-MS quality control processes.
  • Continuous synthetic oligonucleotide method and process development.
  • Solid decision-making on product path with the ability to work independently and collaboratively while problem-solving.
  • Demonstrate lab competency in preparing reagents and buffers & handling chemicals.
  • Write and follow standard operating procedures and process improvement documents.
  • Documentation of results and data analysis.
  • Ensure safety and product quality are paramount throughout the laboratory environment.

  • Ph.D. in Chemistry, Biochemistry, Biochemical or Chemical engineering or related discipline with at least 2 years experience, preferably in an industrial drug discovery setting.
  • MS with 8 years and BS with 10 years of experience will also be considered.
  • Basic computer skills including MS Office Suite.
  • Attention to detail
  • Exceptional time management
  • Effective communicator
  • Capable of repetitive tasks and performing other duties as assigned


EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.