Associate Director, Biomarker and Bioanalytical Sciences

Location
San Diego, California
Posted
Mar 29, 2021
Ref
o5CLefwq
Hotbed
Biotech Beach
Required Education
Doctorate/PHD/MD
Position Type
Full time

Associate Director, Biomarker and Bioanalytical Sciences

Location: La Jolla, CA

Position type: Research and Development

Description:

We are seeking an experienced scientist to lead biomarker development for several research and development programs at Avidity Biosciences in La Jolla, CA.  This is a key position within the Biomarker and Bioanalytical Sciences team that will contribute to preclinical and clinical biomarker strategy, assay development, and implementation.  The ideal candidate will have a proven ability to identify, develop, and implement clinical biomarker strategies in the pharmaceutical industry. Experience with transfer of biomarker methods to external service providers and familiarity with validation standards for clinical biomarker development is highly desired.  The ideal candidate is expected to be a strong team player and leader who enjoys scientific discovery and can communicate and collaborate in a fast-paced interdisciplinary environment.

Responsibilities:

  • Identify and develop novel biomarkers to support preclinical and clinical projects
  • Lead a team of scientists to efficiently design, execute, analyze, and report experiments that support biomarker identification and method development
  • Experience with gene expression technologies in the clinical setting highly desired
  • Manage relationships with external service providers, including method transfer, method development, method validation, and sample analysis in a GLP environment
  • Collaborate and communicate across departments, participate on drug development project teams, and function as a bridge between preclinical and clinical development
  • Demonstrate effective presentation and verbal communication at internal meetings as well as clear written communication

Requirements:

  • PhD in Bioengineering, Biology, Biochemistry, or related discipline; with 5+ years of relevant industry experience
  • Thorough knowledge of regulated bioanalysis and biomarkers in nonclinical development, along with translation of those assays into clinical development
  • Desirable for applicant to be familiar with bioanalytical method development and validation of biomarkers commensurate with regulatory decision making or supporting approval and labeling
  • Prior hands-on experience with various laboratory techniques including tissue homogenization, RNA isolation, RT-qPCR, HPLC, ELISA, Nanostring, and RNA-seq
  • Ability to conduct self-directed research and to work effectively in a dynamic environment with a diverse team of coworkers
  • Solid written and oral communication skills, enthusiasm, integrity, exceptional problem-solving skills, self-motivation, strong interpersonal skills, and attention to detail are necessary