Scientist, Immunology and Biology

 Avidity Biosciences is pioneering a new class of oligonucleotide-based therapies called AOCs designed to overcome the current limitations of oligonucleotide therapies in order to treat a wide range of serious diseases. We utilize our proprietary AOC platform to design, engineer and develop therapeutics that combine the tissue selectivity of monoclonal antibodies (mAbs) and the precision of oligonucleotide-based therapies in order to access previously undruggable tissue and cell types and more effectively target underlying genetic drivers of diseases. We are passionate about the impact of every employee in bringing these potentially transformative therapeutics to patients in need. Make a difference with us.

We are seeking a highly motivated and independent immunologist to join our team. The candidate should be a cellular immunologist with experience studying lymphocyte and myeloid cell function in multiple diseased models. The candidate will be responsible for the design, execution, data analysis, and presentation to multidisciplinary teams and senior management.

• Conduct in vitro and in vivo assays with human and rodent immune cells
• Perform cell killing, suppression, and proliferation assays
• Develop flow cytometry assays
• Perform immunohistology assays, as well as conduct other standard molecular and cellular techniques
• Ability to design, perform and interpret complex experiments
• Strong organizational skills, including the ability to manage several projects simultaneously
• Proficient computer and data analysis skills
• Clear and professional verbal and written communication
• Must be able to work independently and in a project team-oriented environment
• Perform other duties as required.

Qualifications

To perform this role successfully, an incumbent must be able to perform each essential duty satisfactorily. The preferred requirements listed below are representative of the skills, knowledge, and/or abilities required.  Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.

Preferred Education and/or Experience

• A Ph.D. degree in biological sciences with 0-5 years of post-doctoral experience, and relevant peer-reviewed publications
• Expertise in evaluating immune cell function in vitro. Experience with proliferation, killing, and suppression assays
• Experience in testing immune cell function in tumor spheroid models is a plus
• Proficiency in flow cytometry, histology, and standard cellular and molecular biology techniques
• Experience with NanoString and single-cell RNAseq is a plus
• Demonstrated strong skills in aseptic techniques, proper handling of chemotherapeutics and protein biologics, and data collection and analysis.

Physical Requirements/Demands

• Remaining in a stationary position, often standing or sitting for prolonged periods.
• Moving about to accomplish tasks or moving from one station to another, or from one worksite to another.
• Adjusting or moving objects up to 10, 25, 50 pounds.
• Communicating with others to exchange information.
• Repeating motions that may include the wrists, hands and/or legs.
• Repeating motions of fingers (typing and/or writing).
• Operating machinery or equipment. [HPLC, pill press, pipettes, copiers, etc.]
• Assessing the accuracy, neatness and thoroughness of the work assigned.
• Ability to use a computer.

Environmental Conditions

• Low temperatures.
• High temperatures.
• Noisy environments.
• No adverse environmental conditions expected.
• Exposure to general laboratory environment conditions.
• Exposure to general office environment conditions.