Senior Associate Scientist - Structural Biology

South San Francisco, CA, US
Mar 28, 2021
Required Education
Position Type
Full time
Amgen is a leading global biotechnology company, with a mission to serve patients. As a science-based, patient-focused organization, we discover and develop innovative therapeutics to treat serious illness. Our medicines have made a dramatic difference in the lives of millions.

We are seeking a senior associate scientist to join the Structural Biology Department at our site in South San Francisco, CA. The Structural Biology laboratory provides comprehensive molecular insights and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various therapeutic areas. The scientist will be part of a growing structure biology group and will be responsible for designing and purifying target proteins for X-ray crystallography and cryo-electron microscopy, data collection and structure determination of complex molecular structures.

Basic Qualifications:

Master's degree and 3 years of structural biology experience


Bachelor's degree and 5 years of structural biology experience

Preferred Qualifications:
  • Knowledge of state-of-the-art X-ray crystallography including construct design, expression, purification, characterization, crystallization, structure determination and modelling.
  • Research experience in large macromolecular complexes.
  • Experience in single particle cryo-EM technology including grid freezing and screening, data collection and processing, three-dimensional reconstruction and model building.
  • Excellent presentation skills (written and oral) that improve team-based collaboration.
  • Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment.
  • Skills in managing multiple projects and capabilities to prioritize.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.