Chemist - Oligonucleotide

Location
Gaithersburg, MD
Posted
Mar 26, 2021
Required Education
Masters Degree/MBA
Position Type
Full time

We are seeking synthetic chemist candidates with experience in phosphoramidite synthesis to fill a newly created position. The successful candidate will be deeply experienced with performing efficient oligonucleotide synthesis using DNA/RNA synthesizers and experienced in downstream purification of the oligos.

The successful candidate will prepare synthetic RNA and chemically modified synthetic RNA oligonucleotides using DNA/RNA synthesizers on demand and perform downstream purification and characterization of the oligonucleotides by cartridge, HPLC, and other methods. This person will also analyze data using analytical instruments including NMR, DLS, HPLC, MS. UV/vis, etc., and maintain detailed documentation records and batch records, and other materials to facilitate tech transfer and regulatory submissions.