Senior Development Associate I

Employer
Lundbeck
Location
Bothell, WA, United States
Posted
Mar 24, 2021
Ref
1756
Hotbed
BioForest
Required Education
Other
Position Type
Full time

Do you want to join a team where the mission is meaningful, the challenges are complex, and you can directly see the results of your hard work? Lundbeck Seattle BioPharmaceuticals (Lu-SBP), located in Bothell, Washington, is the Process Development Center of Excellence for Biologics within the global Lundbeck CMC organization. Since integrating into Lundbeck in October 2019, Lu-SBP has supported commercial launch of Lundbeck's first biologic product (Vyepti) and advancement of a growing biologics pipeline in collaboration with our Copenhagen-based Late-Stage Development and Production groups. The Lu-SBP team leads and supports the development of new product candidates from cell line development through commercial validation of Drug Substance and Drug Product manufacturing processes. Join us on our journey of progress & innovation dedicated to addressing the vast unmet medical needs associated with brain disease!

SUMMARY:

The Downstream Process Development group is seeking an individual to be part of a team developing expression and purification processes for antibody candidates supporting preclinical and clinical development. The primary responsibility is to rapidly identify scalable purification methods for new antibodies and support these processes to clinical scale.

ESSENTIAL FUNCTIONS:

  • Screen lead antibody and cell line candidates for appropriate development characteristics
  • Purify and formulate antibody preparations to support analytical and pre-clinical studies
  • Collaborate in purification development from multiple expression platforms
  • Perform purification process transfer internally and externally
  • Design and execute purification screening, scouting and characterization experiments
  • Work collaboratively with upstream process development and analytical development groups
  • Creates written reports on experimental design, analysis and conclusions, and deliver presentations on findings

 


REQUIRED EDUCATION, EXPERIENCE and SKILLS:

 

 

  • Accredited Bachelor's degree and 5+ years' experience in biopharmaceutical industry or relevant combination of education and experience totaling 9+ years
  • Extensive experience purifying proteins using column chromatography
  • Skilled in Unicorn-based AKTA programming and result evaluation.

 


PREFERRED EDUCATION, EXPERIENCE AND SKILLS:

 

 

 

  • Accredited Bachelor's degree or Master's degree in biochemistry, chemistry or related discipline
  • Strong resin chemistry knowledge
  • Familiarity with antibody purification scale-up and manufacturing considerations
  • Wide background in protein analytical techniques
  • Labkey familiarity
  • Experienced with plate-based screening methods
  • Octet and Surface Plasmon Resonance experience
  • Working knowledge of JMP statistical analysis software

 


Why Lundbeck

Lundbeck is unique from other biopharmaceutical companies in that we are 70 percent owned by a research-focused foundation. We have a deep heritage of discovery and have brought breakthrough therapies to millions of people across the globe. And we're just getting started! Our success is driven by our great people and inclusive culture, which is guided by our beliefs of being Patient-Driven, Courageous, Ambitious, Passionate & Responsible. Are you ready to make an impact, one patient at a time?

Lundbeck offers a robust and comprehensive benefits package to help employees live well and protect their health, family, and everyday life. Information regarding our benefit offering can be found on the U.S. career site .

Lundbeck is committed to working with and providing reasonable accommodations to disabled veterans and other individuals with disabilities during our employment application process. If, because of a disability, you need a reasonable accommodation for any part of the application process, please visit the U.S. career site .

Lundbeck is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, and any other characteristic protected by law, rule, or regulation. Lundbeck participates in E-Verify .

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Lundbeck is a global pharmaceutical company specialized in brain diseases. For more than 70 years, we have been at the forefront of neuroscience research. We are tirelessly dedicated to restoring brain health, so every person can be their best.

Millions of people worldwide live with brain diseases, and far too many suffer due to inadequate treatment, discrimination, a reduced number of working days, early retirement, and other unnecessary consequences. Every day, we strive for improved treatment and a better life for people living with brain diseases - we call this Progress in Mind.

Read more at www.lundbeck.com/global/about-us/progress-in-mind

Our approximately 5,800 employees in more than 50 countries are engaged in the entire value chain throughout research, development, production, marketing, and sales. Our pipeline consists of several R&D programs, and our products are available in more than 100 countries. We have research centers in Denmark and the US, and our production facilities are located in Denmark, France, and Italy. Lundbeck generated revenue of DKK 17 billion in 2019 (EUR 2.3 billion; USD 2.6 billion).

For additional information, we encourage you to visit our corporate site www.lundbeck.com, and connect with us on Twitter at @Lundbeck and via LinkedIn.