Amgen

Senior Scientist -Discovery Attribute Sciences

Employer
Amgen
Location
Thousand Oaks, CA, US
Posted
Mar 24, 2021
Ref
R-111971
Required Education
Other
Position Type
Full time
HOW MIGHT YOU DEFY IMAGINATION?

If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together-researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It's time for a career you can be proud of. Join us.

Senior Scientist -Discovery Attribute Sciences

Live

What you will do

Let's do this. Let's change the world. In this vital role you will a part of the Discovery Attribute Sciences within Amgen Research providing scientific and technical expertise to support early discovery research through to later stage molecule optimization and late-stage selection of Amgen's pipeline of drug candidates. This position is an exciting opportunity to unlock the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics.
  • Identifying and assessing a variety of manufacturability and quality attributes of therapeutic protein candidates utilizing multiple analytical techniques.
  • Develop and apply novel sample preparation and analytical methods for the analysis of therapeutic proteins to assess biophysical properties such viscosity, aggregation and charge heterogeneity with emphasis on techniques such as size exclusion chromatography, hydrophobic interaction, ion exchange chromatography, formulation screening, calorimetry and multiple protein viscosity measurements and mass spectrometry analytical techniques.
  • Investigation, development and the application of miniaturized, predictive and high throughput protein stability and manufacturability methods is expected.
  • The expectation for this role is to be predominantly laboratory based, providing support for multiple projects and their advancement and also be able to perform innovative manufacturability and attribute technology application method development.
  • Excellent demonstration of communication (verbal and in written) of scientific concepts and results.
  • Work collaboratively and lead other scientists on multidisciplinary teams.
  • Work independently and in teams in advancing projects and studies within required deadlines.
  • Actively create or contribute to patents and publications. Demonstrate external scientific eminence in the form of peer-reviewed publications and conference presentations.
  • Keep current with field of expertise, participate and advance drug development, technologies and information services programs within Amgen.
  • Follow protocols and procedures, maintain accurate records in an electronic lab notebook, and generate quality data for use in drug development


Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientific professional we seek is a proven leader with these qualifications.

Basic Qualification

A Doctorate degree with 5+ years in Analytical Chemistry, Biochemistry or equivalent with emphasis in mass spectrometry and other analytical characterization techniques, such as reversed-phase, size exclusion chromatography, capillary electrophoresis, rheology and calorimetry.

Relevant experience working as part of a multidisciplinary team in a biopharmaceutical setting would also be an advantage.

Preferred Qualifications
  • Documented theoretical knowledge and hand-on experience in assessing molecule stability and manufacturability using both traditional analytical techniques and high throughput predictive methods would be preferred.
  • Training and experience of operating Agilent and Waters HPLCs and UPLCs and formulation screening measurements would be advantageous.
  • Proficiency with Microsoft Office. Knowledge of statistical processing of data, including related software like Excel, Spotfire, JMP or ArrayStudio and chromatographic software control and data processing packages is required.


Thrive

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates' professional and personal growth and well-being.
  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits


Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

careers.amgen.com

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.