Research Associate III, Discovery Chemistry

Location
San Francisco, CA, United States
Posted
Mar 19, 2021
Ref
5330-192-2021
Hotbed
Biotech Bay
Required Education
Other
Position Type
Full time
Position Overview

Nektar Therapeutics has an exciting opening for a Research Associate III to join our Discovery Chemistry group.

We are seeking a talented synthetic, organic chemist to support the company's research and development efforts to create high value therapeutics to address unmet medical needs.

Responsibilities

The successful candidate will:
  • Under general supervision, design and safely synthesize, purify and characterize cleavable and non-cleavable linkers and apply them to bioactive molecules for the development of novel therapeutics.
  • Participate in the development of Nektar's polymer conjugation technology and incorporate polymers into linker designs.
  • Efficiently deliver compounds/polymer conjugates for biological testing or use in developing therapeutics.
  • Carry out process development experiments to enable the technology transfer of new scalable and cost-effective routes to linkers and intermediates.
  • Maintain accurate and well-organized laboratory records and notebooks
  • Under general supervision, develop approaches and experiments to address complex problems with sound judgment, using multiple data sources and drawing general, non-obvious conclusions.
  • Plan and coordinate activities with other team members.
  • Interface with various departments, customers and partners, putting work practices into context with larger teams.
  • Write reports and protocols.
  • Maintain current training requirements and ensure adherence to company policies and quality requirements.
The successful candidate may:
  • Facilitate the design of new residue selective linkers by interacting with other chemists and interdisciplinary team members to optimize DMPK, in vitro, and in vivo pharmacology properties.
  • Assist with implementing organizational systems, identifying capital equipment, and projecting near-term resource requirements.
Minimum Qualification Requirements

A Bachelors or MS degree in Organic or Medicinal Chemistry. A minimum of 5 or more years of work experience in a pharmaceutical research and/or development environment is required.

The successful candidate must be willing and able to:
  • Demonstrate hands-on technical proficiency, scientific creativity, collaboration with others and sound judgement.
  • Demonstrate strong organizational skills.
  • Demonstrate knowledge of scientific principles and concepts.
  • Work as part of an interdisciplinary team, demonstrating good interpersonal skills.
  • Clearly communicate scientific information, both written and oral, with the ability to present technical information to both technical and non-technical audiences.
  • Demonstrate good computer skills; a working knowledge of MS Word, Excel, PowerPoint and CambridgeSoft ChemOffice is required.
Employees must be able to lift or handle objects greater than 25 pounds to perform certain duties essential to the job function. Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees must be able to wear a respiratory protection (filtering facepiece, 1/2 face, full-face, or powered air purifying respirator, supplied air, or self contained breathing apparatus) for certain tasks essential to the job function. Employees must be able to able to accurately detect color and have 20/20 vision (with/without corrective lenses). Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function.

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.