Principal Scientist - Protein Technologies

South San Francisco, CA, US
Mar 14, 2021
Required Education
Position Type
Full time

If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together-researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It's time for a career you can be proud of. Join us.

Principal Scientist- Protein Technologies


What you will do

Let's do this. Let's change the world.

Amgen's Therapeutic Discovery organization is seeking an enthusiastic, collaborative Principal Scientist team to lead membrane protein efforts in the Protein Technologies group at our Amgen South San Francisco site. Protein Technologies is responsible for designing, planning and executing on the generation of key enabling DNA and protein reagents to support discovery of small and large molecule therapeutics and cutting-edge novel modalities.

As a team lead within Protein Technologies, you will be responsible for recruiting and managing a high-performing team producing complex membrane proteins to support the Amgen pipeline. You will be responsible for the scientific, strategic and operational management of the group, and will also actively participate in the science through hands-on lab work as well as exploring and implementing enabling technologies. You will be responsible for initiating and driving collaborations with partner functions such as Antibody Discovery, Discovery Technologies, Molecular Structure and the Research Biology organization.

Well-qualified applicants will have a strong scientific background in membrane protein expression, purification, formulation and analytics, and an interest in technology development in this field. They will have demonstrated success in project and personnel management, and be adept at working cross-functionally.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients.

The Principal Scientist we seek possesses these qualifications:

Basic Qualifications

Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or a related discipline and 3 years of industry experience

Preferred Qualifications
  • Ph. D. and postdoc from a leading institution or biotechnology company with 5+ years of related industry experience
  • Deep expertise in membrane protein expression, protein biochemistry, formulation, biophysics and analytics, as evidenced with a track record of innovative strategies towards production of membrane proteins
  • Structural biology experience in membrane proteins is a strong plus, as is expertise in other difficult protein classes
  • Project leadership in biologics drug development as evidenced by peer-reviewed publications, patents, or pipeline contributions
  • 3+ years of managing a high-performing team in industry with a focus on protein/membrane protein expression, biochemistry, biophysics and analytics.
  • Ability to inspire and grow a high-performing team, chart and set team goals into action, prioritize a range of activities and projects, and forge productive cross-site collaborations with partner functions
  • Strong written and verbal communication, including the ability to articulate goals, objectives and results to both the group and to cross-functional teams


What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates' professional and personal growth and well-being.
  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.