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Senior Manager, SEC Reporting

Employer
4D Molecular Therapeutics
Location
Emeryville, CA
Start date
Mar 4, 2021

View more

Discipline
Administration, Accounting, General
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

4D Molecular Therapeutics, Inc. (“4DMT”) is a clinical-stage gene therapy company pioneering the development of product candidates using targeted and evolved AAV vectors. 4DMT seeks to unlock the full potential of gene therapy using its platform, Therapeutic Vector Evolution, which combines the power of directed evolution with approximately one billion synthetic capsid sequences to invent evolved vectors for use in targeted gene therapy products. The company is initially focused in three therapeutic areas: ophthalmology, cardiology, and pulmonology. The 4DMT targeted and evolved vectors are invented with the goal of being delivered through clinically routine, well-tolerated and minimally invasive routes of administration, transducing diseased cells in target tissues efficiently, having reduced immunogenicity and, where relevant, having resistance to pre-existing antibodies. 4DMT is currently conducting three clinical trials: 4D-125 is in a Phase 1/2 clinical trial for XLRP, 4D-110 is in a Phase 1 clinical trial for choroideremia and 4D-310 is in a Phase 1/2 clinical trial for Fabry disease.

4DMT is focused on attracting and retaining the best people in the industry who identify with our mission and innovative results-driven approach. We offer an inspiring and collaborative environment that encourages individual contributions, recognizes performance in multiple ways, offers competitive salary and benefits, and provides challenging opportunities for career development.  4D Molecular Therapeutics is located in Emeryville, CA.

GENERAL SUMMARY:
The Senior Manager, SEC Reporting will be responsible for preparing all SEC filings, serving as the primary contact for the audit and quarterly reviews, leading the technical accounting efforts and assisting with the monthly close.  This is a high profile position that will work cross-functionally with many departments within the company as well as with several service providers including auditors and lawyers.  This position will report to the Controller. 
Responsibilities:
  • SEC Reporting: 40%
  • Compile financial statements (consolidated balance sheet, consolidated income statement, statement of cash flows, statement of stockholders’ equity, footnotes) and other SEC disclosures
  • Prepare EPS calculations
  • Review and approve XBRL tagging of financial statements under US GAAP
  • Prepare tie-out support for all SEC filings
  • Prepare disclosure checklists
  • Ensure financial statements are prepared in accordance with US GAAP and SEC regulations, including newly issued accounting pronouncements
  • Monthly Close: 20%
  • Provide support on the monthly and quarterly closes including preparation of journal entries and reconciliations of more complex or technically challenging balance sheet accounts
  • Technical Accounting: 20%
  • Proactively monitor newly issued accounting pronouncement and manage the company’s timely implementation of relevant pronouncements
  • Identify complex transactions requiring technical analysis and perform research and prepare technical memos on the transactions
  • Manage Audits/Quarterly Reviews: 20%
  • Act as the primary contact for the auditors during the annual audit and quarterly reviews
  • Prepare audit schedules and respond to auditor inquiries
  • Ensure that all PBCs are provided on a timely basis to the auditors 
  • Other duties as assigned

Qualifications
  • Bachelor’s degree required
  • CPA required
  • Experience:
  • 5+ years of related experience required
  • 2+ years of public company experience required
  • Experience with ActiveDisclosure required
  • Big 4/Public accounting experience strongly preferred
  • Biotech industry experience strongly preferred
  • Experience with Intacct and Equity Edge Online strongly preferred
  • Skills:
  • Detail-oriented yet not lost in the details
  • Excellent communication skills, both written and verbal
  • Strong technical accounting background with knowledge of US GAAP, SOX and SEC reporting standards
  • Able to successfully manage multiple projects with competing priorities and tight deadlines
  • Able to produce quality results in an efficient manner
  • Able to work analytically in a problem-solving environment
  • Familiar and comfortable with working in a growing company and able to work with all functions in the organization
  • Physical Requirements
  • Adhere to 4DMT COVID protocols and policy 
  • Until it is deemed safe to return to our Emeryville worksite, this role will be remotely based. 

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran and any other category protected under applicable federal, state, provincial and local laws.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

Company

4DMT is a gene therapy company with a transformative discovery platform --Therapeutic Vector Evolution --that enables our “disease first” approach to product discovery and development, thereby allowing us to customize our AAV vectors to target specific tissue types associated with the underlying disease.


At 4DMT we are creating and developing optimized “biopharmaceutical grade” AAV vectors that will allow us uniquely to unlock the full potential of gene therapy. Our customized and proprietary AAV vectors are each designed, according to a 4DMT Target Vector Profile, to deliver genes to specific cells and tissues in the body to eradicate both rare and large market diseases.


While AAV gene therapy pioneers are making great strides with the first wave of products, hurdles still exist with the use of conventional vectors. The most commonly used AAV capsids (e.g., AAV2, 5, 8 and 9) were identified either 1) as contaminants in lab stocks of adenovirus, or 2) through monkey tissue processing. Therefore, these conventional vectors are not targeted specifically to any tissue in the body. This can lead to inefficient and non-specific delivery, thus requiring extremely high doses and potentially resulting in toxicities (including inflammation), high manufacturing burdens and suboptimal efficacy. In addition, suboptimal routes of delivery can be required for delivery to the right tissues (e.g., subretinal delivery to the retina). Finally, pre-existing neutralizing antibodies in many patients can limit efficacy, clinical trial enrollment and market sizes. 4DMT Innovation empowers us to create new and improved next generation AAV capsids to allow targeted delivery of our products by the optimal clinical route of administration.


At 4DMT we use our robust discovery platform, termed “Therapeutic Vector Evolution,” to create customized and proprietary gene delivery vehicles (novel AAV vectors) to deliver genes to specific tissues and cells in the body by the optimal route of administration. We use the power of evolution to create and refine these optimized vectors through genetic diversification and then natural selection in vivo.


4D Purpose Statement:  Boldly Innovating to Unlock the Full Potential of Gene Therapy for Countless Patients


GUIDING PRINCIPLES

 

  • Dare to Cure - Patients are waiting. Create big dreams for patients and take calculated risks to achieve them
  • Break Boundaries - Question the status quo and innovate beyond conventional approaches
  • Beyond Yourself - It's about patients, their families, our team, our families. We strengthen each other.
  • Prepare and Execute Relentlessly - Start with the end in mind, over-prepare and make contingency plans to your contingency plans


We invite all of you who share our passion and vision in creating the ultimate gene therapy products to cure genetic and rare diseases in children and adults. We seek the best people in the industry who identify with our mission and innovative results-driven approach. We offer an inspiring and collaborative environment that encourages individual contributions, recognizes performance in multiple ways, offers generous benefits and provides challenging opportunities for career development. 
 

Company info
Website
Phone
510-505-2680
Location
5858 Horton St. Suite 455
Emeryville
California
94608
United States

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