2021 Tau Pathobiology Co-op

Cambridge, MA, United States
Feb 25, 2021
Required Education
Bachelors Degree
Position Type
Full time

About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

Tau misfolding plays a key role in Alzheimer's disease (AD), as well as other neurodegenerative diseases. There has been an explosion in novel science related to the release, spread, and uptake of tau aggregates in pathology conditions by numerous in vitro and in vivo approaches. We are interested in understanding the characteristics of tau aggregates which are responsible for the seeding and propagation of pathology. The student will help to perform and analyze in vitro biochemical experiments to characterize the human AD brain isolated tau aggregates. In particular, student will work on developing novel pathological tau assays using digital ELISA platform - SIngle MOlecule Array (SIMOA) and also works with OCTET based on Bio-Layer Interferometry (BLI) technology to determine the real-time, label-free kinetics and affinity of proprietary antibodies.

We are seeking a student who is highly motivated, hard-working, detail-oriented with good communication skills. Experience with one or more of the following skills is preferred but not required: ELISA or Western blot or any immunoassays or biochemical assays.



  • Desired Majors:Biochemistry, Molecular Biology, Neuroscience

    Basic Qualifications:
  • Completed at least one year of college education before beginning internship
  • Must be enrolled in school the semester following your internship
  • BS/BA student
  • Minimum GPA: 3.0/4.0
  • Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship
  • School and/or work experience using Microsoft Word, Excel and PowerPoint

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Job Type
Job Level Code
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.