Vice President, Genome Engineering
- Employer
- Mammoth Biosciences
- Location
- Brisbane, CA, United States
- Start date
- Feb 24, 2021
View more
- Discipline
- Science/R&D, Genomics
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
DESCRIPTION
Mammoth is seeking a VP of Genome Engineering that will be responsible for driving Mammoth next-generation CRISPR proteins from discovery to clinical development. The role will involve managing the genome engineering team while also being the main point of contact between external research partners and CROs. The person will work closely with company leadership to set research priorities. A deep understanding of quality, manufacturing and regulatory processes in gene editing is essential.
KEY RESPONSIBILITIES
- Lead research and pre-clinical development aspects of Mammoth's genome engineering portfolio
- Lead genome engineering animal studies utilizing Mammoth's CRISPR portfolio
- Recruit and coach technical team leads to form a strong and cohesive unit
- Oversee and manage the technical relationships with external partners
- Work with the business development team to gather, organize, and prioritize R&D efforts
- Plan and coordinate the creation of new genome engineering modalities
- Implement project management approaches
- Project budgeting and scope management
- Work with operations in the scale up of materials and processes (with external partners as appropriate)
- Play a strong supporting role in development and maintenance of quality system and regulatory planning
- Proactively identify potential risks/issues and work with the team to develop mitigation strategies.
- Work with scientific advisory board and KOLs to refine R&D strategy
REQUIRED QUALIFICATIONS
- MD or PhD
- Minimum of 10 years professional experience in clinical development of gene therapies or genome engineering technologies
- Experience leading IND submission of gene editing or gene therapy product
- Extensive experience building and managing teams
BENEFITS
- Company-paid health/vision/dental benefits
- Unlimited vacation and generous sick time
- Company-sponsored meals and snacks
- Wellness, caregiver and ergonomics benefits
- 401(k) with company matching
Company
Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.
- Website
- http://www.mammoth.bio/
- Phone
- (650) 294-8583
- Location
-
South San Francisco
CA
94080
United States
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