Senior Director, In Vitro Biology

Magenta Therapeutics is a clinical-stage biotechnology company developing therapeutics to reset the immune system to cure more patients with devastating and life-threatening diseases. This immune reset approach can be realized through stem cell transplant for multiple diseases, including autoimmune diseases, blood cancers and genetic diseases.

Magenta's comprehensive approach to precision immune system reset will transform many aspects of the transplant process, aiming to make it safer and more effective. Our culture is fueled by a driven, passionate group of people committed to making a difference, seizing opportunities for maximum impact, and pursuing progress for the patients we seek to serve.

We are seeking an expert in Immunology and/or stem cell biology who is excited to identify and validate new targets for the conditioning phase of stem cell transplant. This position will report to the CSO & Head of Research and will be responsible for the identification and validation of new targets and the in vitro support of the current Discovery and Development pipeline. If you are looking for a place where you can impact the strategy of the company, while remaining close to the lab and the science, we would like to hear from you.

You are perfect for this role if you are engaged by and want to be responsible for:

• New target identification, validation, screening for bioactive molecules
• Responsible for the generation of in vitro data packages to support advancement of projects into development
• Leading a group of talented discovery scientists
• Leadership of Discovery projects through IND
• Interacting and collaborating with scientists across Discovery and Development

We would be thrilled if you brought the following with you:

• PhD degree required in a relevant field (Immunology or Stem Cell Biology) with a minimum of 8 years' experience including some previous industry experience
• Experience with human in vitro cellular techniques including:
• primary human cell culture (experience working with Immune cells and/or Hematopoietic stem cells desirable)
• molecular techniques for identification of new targets such as ssRNAseq, Cite Seq etc.
• multi-parameter flow cytometry including cell separation/sorting
• functional assays of stem cell and/or immune cell function
• Must be a creative, organized, strategic, motivated self-starter, capable of driving a portion of the discovery strategy.
• Experience leading a group and collaborating effectively within cross-functional teams
• The position requires excellent communication skills and the ability to work in a highly collaborative, fast-paced environment

Successful leaders and contributors within Magenta are:

• Driven. You will be focused on the achievement of Magenta's mission and major corporate goals.
• Results-focused. Demonstrated record of exceeding stretch goals, and willing to bring creative problem-solving skills to challenges along the way
• Intuitive. You will enjoy learning and being involved in the content of our whole business, thriving on a very fast-paced and growing business
• Collaborative. You will have demonstrated the ability to achieve objectives across complex projects and organizational structures
• Process-oriented, yet flexible. You will appreciate and be able to create and drive process, while also recognizing when flexibility is needed.
• Transparent and Articulate. You will have the ability to communicate clearly and concisely with all stakeholders
• Independent. You will be able to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the company
• A role model for the company's cultural pillars; Courage, Commitment & Excellence

At Magenta, we celebrate our differences. We value the power of a diverse array of folks who bring all of themselves to their work. We embrace cultural, cognitive, social, and professional diversity because we know the only way we're going to make new cures possible is by working together.