Research Associate - Analytical Method Development

At Miltenyi Biotec, 3,000 employees worldwide develop pioneering solutions for biomedical science and the clinical application of cell therapies.  On our Process Development team, we work to ensure that lentiviral vectors for multiple therapeutic indications can be produced in a scalable, serum-free suspension production system. Due to the many clinical successes using our lentiviral vector, activities to characterize and validate our manufacturing processes are underway. This, coupled with our expansion into our new facility gives us the opportunity to grow our team with talented process development professionals.

Your Tasks:

As a member of the Lentigen Technology Process Development team, you will have the exciting opportunity to support the development, characterization, and tech transfer of processes to manufacture purified lentiviral vectors used for pre-clinical and clinical gene therapy products. You will apply your analytical experience to support quantitation and characterization of Lentiviral vectors produced within Process development. This may also include execution of cell culture and purification based experiments with a focus on characterizing viral vector production. Your superb organizational and documentation skills will be instrumental in the tracking and communication of data and will ensure efficient progress towards achieving team objectives. In addition to your primary responsibilities, you will order necessary supplies, maintain laboratory equipment and space, prepare buffers, and train team members as needed. Overall, your attention to detail and keen ability to reliably perform analytical assays and methods in a cross-functional team will champion the continued development of Lentigen Technology’s new products and growing success.

Your Profile:

• A degree in the life sciences with two years’ experience; or equivalent combination of education and experience.
• Experience performing assays and methods, including cell-based assays, qPCR, ELISA, HPLC, and SDS-PAGE.
• Familiarity and/or working knowledge of Flow Cytometry, qPCR/ddPCR, Western-blot, HPLC, Total Protein/Nucleic acid quantitation methods, with cell culture experience a plus. Nanoparticle analysis technologies are desired but not mandatory (DLS, MALS, NTA, TRPS)
• Developing, qualifying and troubleshooting assays and analytical methods, with GxP experience a plus. 
• Superb documentation and organizational skills, often providing summaries and generating development reports to support technical transfer to Manufacturing and Quality Control departments.
• A firm grasp of statistical analysis, with experience in DOE and JMP software a plus. 
• Proficient in the use of Microsoft Office products, particularly Word, Excel, and Powerpoint. 

Physical Requirements:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to walk; use hands to finger, handle, or feel; reach with hands and arms, talk, and hear. The employee is required to stand; climb or balance and stoop, kneel, crouch. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have the ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail.

Work Environment:
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. This job is performed in a temperature controlled facility without exposure to extreme hot or cold temperatures. Generally, this job is performed in a sanitized laboratory setting and routinely uses standard medical and research equipment such as biosafety cabinets, CO2 incubators, centrifuges, pumps, bioreactors, microscopes, and computers. While performing the duties of this job, the employee is frequently exposed to blood, viruses, bacteria, body fluids and other tissues. Employees entering and leaving the laboratory must wear appropriate clothing and protective equipment such as masks, glasses, and gloves. The noise level in the work environment is usually moderate.

Lentigen Technology Inc., a Miltenyi Biotec company, is transforming and progressing. Our culture is one of bold scientific innovation. Join a fresh and collaborative working environment that encourages contribution, innovation, and growth.

At Lentigen, we support the development and commercialization of novel treatments for human disease through the utilization of lentiviral vectors. We hold this widely recognized and clinically relevant method for delivering genetic materials into cells in order to modulate their function as a core strength of our company. We are scientists, engineers, physicians, support specialists, and more – all dedicated to improving scientific understanding and impacting human lives. At our Gaithersburg campus, we strive to find solutions to both the technical and conceptual barriers to the implementation of gene therapy approaches for the treatment of human disease.

Lentigen Technology, Inc. is an EO Employer – M/F/Veteran/Disability/Sexual Orientation/Gender Identity