In Vivo Scientist

South San Francisco, CA
Feb 15, 2021
Required Education
Position Type
Full time

Yoh Life Sciences is seeking a In Vivo Scientist for a Therapeutic client in South San Francisco. This is a full-time direct hire opportunity.

See below for complete job responsibilities and requirements. If after reviewing, you are interested in learning more about this, or other opportunities within the Life Sciences Industry, please apply with your updated resume. 

Title: In Vivo Scientist
Pay Rate: 100-125K depending on years of industry experience
Location: South San Francisco
Type: Direct Hire with our client


In vivo scientist



Minimum qualifications for successful candidates:

  • Ph.D or equivalent in developmental biology, immunology, or related field
  • Minimum 3-5 years of postdoctoral experience in a laboratory setting
  • PhD/DVM preferred
  • Hands-on experience: handling immunocompromised animal/murine models, injections (i.e. IP, IV, IA, SC), small animal surgery, blood and tissue harvesting and processing for downstream analysis and experimental applications
  • Demonstrates ability to run in vivo studies in an independent manner and to assist in the design and execution of non-routine in vivo experiments.
  • Experience in isolation and processing of hematopoietic tissues from animal models, particularly preparation of bone marrow cells involving dissection, generation of single-cell suspensions, red blood cell lysis, viable-cell quantification
  • Processing of primary human bone marrow/peripheral blood/cord blood samples, isolation of PBMCs (eg. Ficoll, MACS)
  • High level of proficiency operating multi-color flow cytometry analysis (FACS) of mouse/human-derived peripheral blood and bone marrow samples (BD platform preferred; BioRad platform a plus); operating FACS sorters a plus (BD Diva-based sorters); highly proficient in DIVA and FlowJo software
  • Responsible for data analysis and interpretation, troubleshooting, and follow up experiment for in vivo projects
  • Good communication skills and experience to writing protocols, procedures, and technical reports
  • Excellent organizational skills, ability to multi-task and work cross-functionally.


Desired / Preferred qualifications for successful candidates:

  • Manage CROs regarding experimental design, implementation and execution of in vivo studies
  • Experience in common molecular and cell biology techniques, histology, cell culture and cloning
  • Experience with in vitro culture of cell lines and primary donor-derived cells (mouse and/or human)
  • Background in orthopedic diseases
  • Various small animal surgery techniques, eg. peripheral blood sampling, retro-orbital/intra-femural transplantation